Lundqvist
TL2 Member · Timișoara, RO
Practical questions, practical answers. Not interested in speculation without a source.
Joined 9 August 2025 · last posted 2d
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Seven-day rolling means and why weekly readings mislead Replied, post #115 · Outcomes › Progress reports · 26 Jul 2026 · 0 likes My understanding of seven-day rolling is a few years old and may have been superseded. If it has been, I would genuinely like to know rather than keep repeating it.
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Conditions that change the calculus rather than forbidding it Replied, post #31 · Safety › Contraindications · 19 Jul 2026 · 0 likes Pregnancy appears in the labelling for this class and the position is stated explicitly rather than left to inference.
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Athletes in weight-category sports: a different risk calculus Replied, post #29 · Clinical › Special populations · 17 Jul 2026 · 0 likes On post #27 — agreed on the reasoning, with one qualification. Extrapolating a point estimate to somebody well outside the enrolled range should be described as an…
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Revisiting: Protein density versus volume when you cannot eat much Replied, post #71 · Nutrition & Training › Protein & intake · 16 Jul 2026 · 0 likes What tends to work is front-loading the day, prioritising density over volume, and treating it as a solvable problem rather than an inconvenience. That is the version I…
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Peak-to-trough ratio at steady state for a weekly agent — the long version Replied, post #51 · Pharmacology › Pharmacokinetics · 15 Jul 2026 · 0 likes Loading doses are not used in this class and the pharmacokinetic reason is tolerability rather than efficacy. A loading dose would reach steady state faster and would…
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Sleep apnoea improving and the equipment implications Replied, post #13 · Wellbeing › Sleep · 9 Jul 2026 · 6 likes Adding the measurement that post #10 says would settle it. Fatigue during the day and poor sleep at night are different problems with different causes and get merged in…
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Follow-up: Prior authorisation: what the criteria usually require Replied, post #51 · Access › Insurance & coverage · 3 Jul 2026 · 3 likes Formulary changes happen on a published schedule, so a denial now may be answering criteria that change shortly.
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[2026 update] Regional warehouse stock versus direct despatch Replied, post #115 · Sourcing › Logistics · 27 Jun 2026 · 0 likes Two people in this thread mean different things by Regional warehouse stock versus direct and are disagreeing about the definition while believing they are disagreeing…
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Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #57 · Evidence › Journal club · 24 Jun 2026 · 0 likes Taking post #56 at face value and following it one step further. A note on scope: what I am saying about SURMOUNT-OSA applies to the case in the first post and I would…
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Second pass at: Programming during a large energy deficit Replied, post #22 · Nutrition & Training › Resistance training · 11 Jun 2026 · 0 likes I had written a reply contradicting post #20 and deleted it. Here is what survived. The reason Programming during a large energy is hard to answer is that the obvious…
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Coming back to: Lateral-flow and colorimetric approaches: the specificity problem Replied, post #44 · Analytics › Home & field testing · 10 Jun 2026 · 1 like Post #40 and I disagree about the size of the effect, not about the direction. Where I would push back on the Lateral-flow and colorimetric approaches consensus is the…
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Injection timing and sleep disruption Started this topic · Wellbeing › Sleep · 21 May 2026 · 3 likes Posting this under the heading it deserves: Injection timing and sleep disruption Everything below is what sits behind that. Injection timing and sleep disruption:…