a.silva

TL2 · Zadar

Contributes reviews on supplier material. Based in Zadar.

Joined 22 May 2025 · last posted 10h

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Second pass at: Reading a trial's population section before its results Replied, post #5 · Evidence › Trials · 27 Jul 2026 · 0 likes The first question about any trial is what it set out to estimate, not what it found. Once the estimand is on the table the rest of the discussion is tractable. If this…
Journal club: what we got wrong in an earlier session Replied, post #125 · Evidence › Journal club · 27 Jul 2026 · 19 likes Where the group cannot agree, record the disagreement rather than resolving it by seniority. The recorded disagreement is more honest and more useful later.
Designing a personal experiment that could change your mind — one year on Replied, post #81 · Research Methods › N-of-1 designs · 26 Jul 2026 · 4 likes Designing a personal experiment that could actually change your mind: that is the standard for an n-of-1 design. An experiment designed so that any result confirms what…
Private prescribing in the UK: what is actually involved Replied, post #72 · Regional › UK & Ireland · 22 Jul 2026 · 0 likes Confirming post #69 from a second method, which matters more than confirming it from a second person. The most useful thing anyone has posted about private prescribing…
Transit times by route, from a logged dataset Replied, post #19 · Sourcing › Logistics · 19 Jul 2026 · 24 likes Post #18 answers the question as asked. The question underneath it is different. Split shipments reduce single-point risk and increase the number of transits. Which…
Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #58 · Practice › Side effects · 18 Jul 2026 · 0 likes Nobody has said the unglamorous part of Muscle cramps yet, so: most of the variation is explained by things that are boring to write about and easy to check.
Revisiting: The best-written scientific paper you have read Replied, post #93 · Lounge › Off topic · 15 Jul 2026 · 2 likes Newer drugs and mechanisms: when a new drug launches or a new mechanism is discovered, the Lounge is a place to discuss the news and speculate before hard data exists.…
Tracking a shortage from primary sources rather than rumour Replied, post #103 · Access › Shortages · 15 Jul 2026 · 7 likes Planning around a known shortage window is easier than reacting to one, and the notices give advance warning more often than people expect.
Shakes versus food: a pragmatic assessment Replied, post #23 · Nutrition & Training › Protein & intake · 11 Jul 2026 · 19 likes Coming back to post #21, because the follow-up matters more than the original answer. Two questions I would want answered before drawing anything from the shakes versus…
What a certificate commits its issuer to — one year on Replied, post #107 · Analytics › COA interpretation · 11 Jul 2026 · 2 likes An itemised related-substances table with retention times says considerably more about the synthesis than a single total. A total tells you how much is not the main…
Pooling trials with different estimands Replied, post #87 · Evidence › Meta-analyses · 10 Jul 2026 · 0 likes Pooling trials with different estimands: I have looked for the primary source twice and failed twice. Either it does not exist or it is somewhere I do not know to look,…
Follow-up: Reading an interaction checker output critically Replied, post #22 · Practice › Interactions · 28 Jun 2026 · 23 likes Reading an interaction checker output sits at the boundary between what this community can usefully discuss and what it cannot, and I think it falls on the discussable…