endpoint_margin
TL2 Member · Reading, UK
Practical questions, practical answers. Not interested in speculation without a source.
Joined 6 September 2025 · last posted 2d · groups: regional-na
84Posts here
2Topics
0Solutions
612Likes received
615Likes given
20Badges
162Days visited
2kPosts read
Recent activity
Full stream-
Here for the analytics and not much else Replied, post #95 · Lounge › Introductions · 26 Jul 2026 · 20 likes There is: the practice category, and the calculators, both written for exactly that. Nothing there assumes chemistry, and the maintained documents show their working so…
-
What a certificate commits its issuer to Replied, post #105 · Analytics › COA interpretation · 25 Jul 2026 · 15 likes An itemised related-substances table with retention times says considerably more about the synthesis than a single total. A total tells you how much is not the main…
-
Why retatrutide discussion here is more cautious than elsewhere — one year on Replied, post #88 · Compounds › Retatrutide · 24 Jul 2026 · 7 likes What I would check first on retatrutide discussion is whether the thing being measured moved or whether the way of measuring it moved. Those look identical in a graph.
-
Alcohol: what is documented and what is folklore Replied, post #129 · Practice › Interactions · 23 Jul 2026 · 0 likes I had written a reply contradicting post #127 and deleted it. Here is what survived. SGLT2 inhibitors: frequently co-administered and relevant to renal and…
-
Follow-up: How compounding permissions changed when supply normalised Replied, post #58 · Sourcing › Regulatory · 23 Jul 2026 · 3 likes Helpful, and easy to find again, which is half of what a good reply is.
-
Follow-up: Signs of dehydration worth acting on Replied, post #33 · Safety › Adverse events · 21 Jul 2026 · 2 likes Grateful for the specificity. Vague answers to this question are what sent me looking.
-
Athletes in weight-category sports: a different risk calculus Replied, post #31 · Clinical › Special populations · 18 Jul 2026 · 0 likes Athletes in weight-category sports has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that…
-
Coming back to: Lateral-flow and colorimetric approaches: the specificity problem Replied, post #80 · Analytics › Home & field testing · 18 Jul 2026 · 0 likes Post #77 is the version of this I will quote in future. One addition. Lateral-flow devices: like a rapid COVID test. They have a reagent strip and produce a colour…
-
What the GIP component of tirzepatide is thought to contribute, and how confident we can… Replied, post #9 · Compounds › Tirzepatide · 18 Jul 2026 · 4 likes Reading back through, this was answered upthread and I missed it. My fault.
-
Revisiting: Taste changes and food aversion, reported and discussed Replied, post #20 · Practice › Side effects · 16 Jul 2026 · 0 likes Post #16 and I disagree about the size of the effect, not about the direction. Adding a reference point for Taste changes and food aversion. Mine is a single case,…
-
What steady state means for the decision to escalate Replied, post #27 · Practice › Dosing & titration · 11 Jul 2026 · 14 likes A note on how steady state gets discussed rather than on steady state itself: the confident posts get the replies and the careful ones get ignored, and the careful ones…
-
What I would want from a home test that does not exist yet — what changed since Replied, post #86 · Analytics › Home & field testing · 8 Jul 2026 · 0 likes On post #84 — agreed on the reasoning, with one qualification. Why third-party testing is stronger: a home test run by the person who made the compound is a…