o.vogel

TL2 · Beirut

Contributes reviews on supplier material. Based in Beirut.

Joined 29 October 2024 · last posted 2d

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Reference intervals: how they are constructed and why one in twenty flags — does this… Replied, post #22 · Clinical › Bloodwork · 26 Jul 2026 · 25 likes Reference intervals is a good example of a question where the honest answer is boring and the interesting answers are unsupported. I would go with boring.
[2026 update] Interpreting a result that disagrees with the supplier's certificate Replied, post #118 · Sourcing › Independent verification · 24 Jul 2026 · 0 likes Post #116 and I disagree about the size of the effect, not about the direction. Small correction to my own earlier position on Interpreting a result. I had the units…
[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #74 · Practice › Interactions · 22 Jul 2026 · 11 likes One more thing on Antibiotics that took me far too long to see: the two figures people quote are not measuring the same quantity. Once you notice that, the apparent…
Primary endpoint hierarchies and why order matters — one year on Replied, post #53 · Evidence › Trials · 20 Jul 2026 · 25 likes Post #51 put the caveat in the right place and I want to underline it. Surrogate endpoints: an endpoint that is not the outcome that matters but is measured as a…
Coming back to: When a red flag was a misunderstanding, and the retraction Replied, post #10 · Sourcing › Red flags · 16 Jul 2026 · 0 likes Thank you for the correction. I would rather find out here than later.
Common supplements people ask about, assessed one at a time Replied, post #37 · Practice › Interactions · 12 Jul 2026 · 0 likes Anyone asking an interaction question should list everything, including the things they consider irrelevant. The irrelevant one is the answer more often than chance…
How much context is too much context in a first post? Replied, post #40 · Start Here › How to Ask · 7 Jul 2026 · 0 likes I read post #38 twice before replying, because I had assumed the opposite. A question about somebody else's post should be a reply to that post, not a new topic. A…
About the Mass spectrometry category Replied, post #6 · Analytics › Mass spectrometry · 4 Jul 2026 · 0 likes A mass match establishes that the measured mass is consistent with the proposed composition. It does not establish purity, sequence order, or the absence of an isomer,…
Journal club: indirect comparison between two programmes, defended and attacked Replied, post #105 · Evidence › Journal club · 3 Jul 2026 · 9 likes The bit of indirect comparison that nobody enjoys is that the answer changes depending on what you are trying to decide with it. Say what the decision is and the thread…
[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #7 · Practice › Interactions · 3 Jul 2026 · 0 likes A supplement is a drug for interaction purposes, and the fact that it is sold without a prescription tells you nothing about whether it interacts. The paperwork is…
Why a glucagon receptor agonist in a weight-loss compound is not a contradiction Replied, post #18 · Compounds › Retatrutide · 29 Jun 2026 · 0 likes Worth separating two things that post #15 runs together. Retatrutide is investigational. Anything obtained outside a trial is by definition research-use-only material…
Tesamorelin has an approved indication — what that changes about the evidence Replied, post #19 · Compounds › Secretagogues & GH axis · 27 Jun 2026 · 0 likes Speaking only to tesamorelin as I have actually seen it, rather than as it is usually described: the effect is real, it is smaller than the thread suggests, and the…