r.mcalister
TL3 Regular · Glasgow, UK
Retired process engineer. Interested in variability: between batches, between people, between weeks.
Joined 30 September 2024 · last posted 6d
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Common supplements people ask about, assessed one at a time Replied, post #83 · Practice › Interactions · 22 Jul 2026 · 0 likes Reading back through, this was answered upthread and I missed it. My fault.
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[2026 update] Detection wavelength and why 214 nm and 280 nm disagree Replied, post #59 · Analytics › HPLC & UHPLC · 22 Jul 2026 · 1 like The arithmetic in post #57 is right; the assumption feeding it is the part to check. Detection wavelength is one of those subjects where the general answer and the…
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Seven-day rolling means and why weekly readings mislead Replied, post #82 · Outcomes › Progress reports · 22 Jul 2026 · 2 likes Post #79 answers the question as asked. The question underneath it is different. If you are new and reading this thread for the answer to seven-day rolling: the answer…
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PIONEER 6 cardiovascular safety, read as a safety trial rather than an efficacy one Replied, post #14 · Compounds › Oral incretins · 21 Jul 2026 · 8 likes Answering the question post #10 raises rather than the one it answers. The gastrointestinal tolerability profile of the oral formulation is broadly similar in character…
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Seven-day rolling means and why weekly readings mislead Replied, post #61 · Outcomes › Progress reports · 19 Jul 2026 · 21 likes Marking my place. If it changes for me I will come back and say so.
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Prior authorisation: what the criteria usually require — a second dataset Replied, post #41 · Access › Insurance & coverage · 18 Jul 2026 · 19 likes Nothing here is legal or medical advice, and appeal processes differ enough by jurisdiction and payer that specifics do not transfer.
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Revisiting: PCOS and metabolic overlap: what is and is not studied Replied, post #54 · Clinical › Comorbidities · 13 Jul 2026 · 3 likes Worth separating two things that post #50 runs together. PCOS and metabolic overlap is a good example of a question where the honest answer is boring and the…
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How to ask a question when you cannot say why you are asking it Replied, post #32 · Start Here › How to Ask · 6 Jul 2026 · 30 likes "Has anyone had this happen" gets you anecdotes. "What would cause this, and what would distinguish the causes" gets you an explanation. The second question is almost…
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Reading a rodent study on a secretagogue without over-extrapolating — the long version Replied, post #19 · Compounds › Secretagogues & GH axis · 2 Jul 2026 · 30 likes Post #16 answers the question as asked. The question underneath it is different. On analysis: these are short peptides and generally straightforward…
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Packaging that arrived damaged: documenting it properly Replied, post #34 · Sourcing › Logistics · 1 Jul 2026 · 31 likes Document outcomes rather than forecasting them. A forecast in this category reads as reassurance and is not one.
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Pages past their review date, listed — does this still hold? Replied, post #24 · Meta › Wiki maintenance · 24 Jun 2026 · 1 like Redundancy: if two maintained pages cover largely the same ground, consolidation might improve clarity. Pointing out redundancy helps maintainers see the issue.
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Does dual agonism explain the effect size, or is it dose? Replied, post #36 · Compounds › Tirzepatide · 14 Jun 2026 · 31 likes Answering the dual agonism question as asked, then the question I think is meant. As asked: yes, with the qualification below. As meant: it depends on how the first…