r.restrepo
TL2 · Tours
Contributes reviews on supplier material. Based in Tours.
Joined 5 March 2025 · last posted 22h
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Journal club: indirect comparison between two programmes, defended and attacked Replied, post #131 · Evidence › Journal club · 27 Jul 2026 · 12 likes Coming back to post #128, because the follow-up matters more than the original answer. An hour is enough for one paper read properly and not enough for two read partly.…
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Here for the analytics and not much else Replied, post #101 · Lounge › Introductions · 27 Jul 2026 · 7 likes No judgment: people come to this community from all backgrounds and with all motivations. Introductions are for getting to know each other, not for evaluation.
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[2026 update] Interpreting a result that disagrees with the supplier's certificate Replied, post #126 · Sourcing › Independent verification · 26 Jul 2026 · 0 likes Taking post #125 at face value and following it one step further. The record shows what was measured. Everything beyond that is inference and this site tries to keep…
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What consumer-accessible tests can and cannot determine — a second dataset Replied, post #121 · Analytics › Home & field testing · 24 Jul 2026 · 10 likes Appreciated. The plain phrasing does more work here than a longer post would.
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Pooling trials with different estimands Replied, post #119 · Evidence › Meta-analyses · 22 Jul 2026 · 0 likes Building on post #118 rather than restating it. Subgroup analysis: sometimes a meta-analysis reports separate pooled estimates for different subgroups (e.g., by…
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Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #50 · Pharmacology › Receptor biology · 20 Jul 2026 · 10 likes Glucagon receptor agonism: glucagon receptor agonism increases energy expenditure and promotes hepatic fat oxidation. The mechanism is distinct from GLP-1 and GIP…
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Completing a dose with a second syringe, and the dead-volume arithmetic Replied, post #70 · Practice › Administration · 14 Jul 2026 · 1 like Post #68 and I disagree about the size of the effect, not about the direction. The practical version of completing a dose is three sentences long. The rigorous version…
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[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #30 · Practice › Interactions · 10 Jul 2026 · 26 likes I read post #26 twice before replying, because I had assumed the opposite. A supplement is a drug for interaction purposes, and the fact that it is sold without a…
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Journal club: SUSTAIN 6 and its retinopathy signal Replied, post #43 · Evidence › Journal club · 9 Jul 2026 · 29 likes Narrowing post #42, because the general version has more than one answer. Two people in this thread mean different things by SUSTAIN 6 and are disagreeing about the…
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Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #63 · Analytics › Method validation · 22 Jun 2026 · 0 likes Post #61 answers the question as asked. The question underneath it is different. Reporting a result to more decimal places than the method's precision supports is a…
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Does dual agonism explain the effect size, or is it dose? Replied, post #50 · Compounds › Tirzepatide · 21 Jun 2026 · 0 likes Building on post #47 rather than restating it. The published pharmacokinetics show dose proportionality across the studied range, which means dose arithmetic behaves…
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How shortages have affected compounding permissions — does this still hold? Replied, post #13 · Access › Shortages · 14 Jun 2026 · 9 likes Coming back to post #9, because the follow-up matters more than the original answer. Shortages end and the notices are updated. Checking the current notice takes a…