sleep_log
TL2 Regular · Tromsø, NO
Sleep, apnoea, and the overlap with metabolic health.
Joined 24 October 2024 · last posted 15h
90Posts here
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Reading a rodent study on a secretagogue without over-extrapolating — the long version Replied, post #66 · Compounds › Secretagogues & GH axis · 27 Jul 2026 · 18 likes Storage: these are lyophilised short peptides and are generally reasonably stable dry and considerably less so in solution. Reconstituting only what will be used within…
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Hair shedding at month three: mechanism and time course — the long version Replied, post #48 · Practice › Side effects · 16 Jul 2026 · 21 likes Building on post #47 rather than restating it. Reading back through the Hair shedding threads from last year, the same three questions come up every time and only one…
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Revisiting: Theoretical plates: useful number or ritual? Replied, post #19 · Analytics › HPLC & UHPLC · 13 Jul 2026 · 0 likes Worth stating the null on Theoretical plates before we explain it: the observation may be nothing. That possibility deserves a sentence and usually does not get one.
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[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #34 · Practice › Interactions · 11 Jul 2026 · 12 likes The arithmetic in post #33 is right; the assumption feeding it is the part to check. One caution on Antibiotics: everything above assumes the underlying documentation…
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Molecular mass of semaglutide and why the figure differs between sources Replied, post #98 · Compounds › Semaglutide · 11 Jul 2026 · 1 like On post #94 — agreed on the reasoning, with one qualification. Semaglutide versus liraglutide in STEP 8: semaglutide produced greater weight reduction and the…
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Reference intervals: how they are constructed and why one in twenty flags — does this… Replied, post #13 · Clinical › Bloodwork · 5 Jul 2026 · 28 likes Two claims get bundled together under Reference intervals and they need separating. The descriptive one — this is what was observed — is usually well supported. The…
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Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #78 · Analytics › Method validation · 5 Jul 2026 · 25 likes A method that reports the same number for every lot is worth a second look. Real processes vary, and a total absence of variation is a statement about the measurement…
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What a reversed-phase purity number actually is Replied, post #18 · Analytics › HPLC & UHPLC · 2 Jul 2026 · 0 likes Worth separating two things that post #14 runs together. Peak purity: a diode-array detector records a spectrum at every time point. If a peak contains two co-eluting…
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Personal or family history of medullary thyroid carcinoma Replied, post #15 · Safety › Contraindications · 25 Jun 2026 · 6 likes Adding the measurement that post #14 says would settle it. Somebody's condition being on a list does not settle the decision, and somebody's condition being absent from…
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Why we ask for units every single time, with three examples of what goes wrong Replied, post #54 · Start Here › How to Ask · 19 Jun 2026 · 0 likes A photograph of a vial is rarely useful and a photograph of a document usually is. Redact the identifiers before you post either.
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Heart failure with preserved ejection fraction: symptom endpoints Replied, post #6 · Clinical › Comorbidities · 19 Jun 2026 · 9 likes Two claims get bundled together under heart failure with preserved ejection and they need separating. The descriptive one — this is what was observed — is usually well…
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Follow-up: Reading an interaction checker output critically Replied, post #8 · Practice › Interactions · 16 Jun 2026 · 9 likes Gastrointestinal symptoms from one compound can mask or mimic an interaction with another. Introducing two changes at once makes attribution impossible, which is an…