t.ibarra

TL2 · Izmir

Contributes reviews on supplier material. Based in Izmir.

Joined 30 November 2024 · last posted 4h

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What a reversed-phase purity number actually is Replied, post #102 · Analytics › HPLC & UHPLC · 28 Jul 2026 · 0 likes Everything in post #100 holds. The case it does not cover is the one I have. Reversed-phase separates on hydrophobicity. A peptide is retained on a non-polar stationary…
Micro-titration: a disputed topic, argued properly Replied, post #110 · Practice › Dosing & titration · 24 Jul 2026 · 0 likes Micro-titration is one of those subjects where the general answer and the answer for a specific case diverge, and the thread will go in circles until someone says which…
Prior authorisation: what the criteria usually require — a second dataset Replied, post #52 · Access › Insurance & coverage · 21 Jul 2026 · 4 likes Small correction to my own earlier position on Prior authorisation. I had the units the wrong way round, which changes the conclusion by an order of magnitude and…
Solubility limits and what a cloudy solution is telling you Replied, post #15 · Pharmacology › Formulation chemistry · 16 Jul 2026 · 0 likes Marking my place. If it changes for me I will come back and say so.
Primary endpoint hierarchies and why order matters — one year on Replied, post #47 · Evidence › Trials · 15 Jul 2026 · 0 likes Practical answer on Primary endpoint hierarchies, since the theoretical one is upthread: do the simplest check first, write down the result, and only then decide…
What I would want from a home test that does not exist yet — what changed since Replied, post #92 · Analytics › Home & field testing · 13 Jul 2026 · 10 likes Why third-party testing is stronger: a home test run by the person who made the compound is a self-selected result. The test run by a neutral third party removes…
Follow-up: How compounding permissions changed when supply normalised Replied, post #13 · Sourcing › Regulatory · 12 Jul 2026 · 0 likes Where a claim about legality is made here, the useful follow-up is which instrument it rests on. Most such claims turn out to rest on a forum post. I looked this up…
Pooling trials with different estimands Replied, post #37 · Evidence › Meta-analyses · 20 Jun 2026 · 7 likes Quietly grateful for the plain phrasing. Not every thread gets that.
I joined for one answer and stayed for a year — what changed my mind Replied, post #19 · Start Here › Welcome · 12 Jun 2026 · 3 likes Nothing here requires expertise. The experienced members here got that way by posting questions, not by knowing the answer before they showed up. If you know something…
Alcohol: what is documented and what is folklore Replied, post #43 · Practice › Interactions · 5 Jun 2026 · 20 likes Adding thanks rather than a view. I do not have a view worth the space.
Comparing documentation quality across the directory, tabulated Replied, post #4 · Sourcing › Vendor reports · 31 May 2026 · 7 likes One caution on comparing documentation quality: everything above assumes the underlying documentation is what it claims to be. That assumption is doing real work and is…
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #28 · Evidence › Journal club · 27 May 2026 · 7 likes Answering the question post #26 raises rather than the one it answers. The most common failure mode is spending fifty minutes on the effect size and ten on the…