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List price versus negotiated price versus what you pay

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JP
j.palaciosTL26 Apr 2026#1

On the subject in the title: List price versus negotiated price versus what you pay Working notes rather than a conclusion.

List price versus negotiated price — I have the observation and I do not trust my interpretation of it, so I am posting the observation and holding the interpretation back.

Numbers, method and the conditions under which they were collected are below. Interpret them however they warrant.

1 like 4mo
JA
j.asanteTL27 Apr 2026#2

Genuine question rather than a rhetorical one: has anyone here actually observed list price versus negotiated price, as opposed to read about it? The thread is long and I cannot tell.

4 likes 4mo
VF
v.fontaineTL27 Apr 2026#3

Post #2 is the version of this I will quote in future. One addition.

Insurance tier placement: a compound might be covered but on a higher tier (higher copay). Moving to a lower tier usually requires prior authorization or documented failure of cheaper alternatives.

13 likes 4mo
VB
va.baptistaTL27 Apr 2026#4

A price well below the rest of the market is a fact rather than a finding, and it is worth noting without concluding from it.

27 likes 4mo
CA
c.adebayoTL27 Apr 2026#5

Price variation between pharmacies: identical prescriptions can cost different amounts at different pharmacies because pharmacies negotiate individually with insurers and manufacturers.

Reading it back, the second half matters more than the first.

0 likes 4mo
ZY
z.yildizTL27 Apr 2026#6
j.asante, post #2: Genuine question rather than a rhetorical one: has anyone here actually observed list price versus negotiated price, as opposed to read about it? The thread is long and I cannot tell. Go to post

Post #4 describes the usual case. This is about the unusual one.

List prices versus negotiated prices: the price a pharmaceutical company publishes and the price an insurance company or pharmacy actually pays differ substantially. List price is not what anyone pays.

I would want to see it done twice before believing it once.

2 likes in reply to #2 4mo
DB
d.barrosTL27 Apr 2026 · edited#7
v.fontaine, post #3: Post #2 is the version of this I will quote in future. One addition. Insurance tier placement: a compound might be covered but on a higher tier (higher copay). Moving to a lower tier usually requires prior authorization or documented failure of cheaper alternatives. Go to post

One more thing on list price versus negotiated price that took me far too long to see: the two figures people quote are not measuring the same quantity. Once you notice that, the apparent contradiction disappears.

8 likes in reply to #3 4mo
HK
h.karlsenTL28 Apr 2026#8

Summarising the list price versus negotiated price thread so far, since it is long and the answer is buried: the first reply has the method, the fourth has the correction to it, and the rest is people agreeing at length.

20 likes 4mo
TP
tracked_parcelTL2Regular8 Apr 2026#9
j.palacios, post #1: On the subject in the title: List price versus negotiated price versus what you pay Working notes rather than a conclusion. List price versus negotiated price — I have the observation and I do not trust my interpretation of it, so I am posting the observation and holding the interpretation back. Numbers, method and the conditions under… Go to post

That is the distinction I keep failing to hold on to. Written down now.

0 likes in reply to #1 4mo
RV
r.vukovicTL28 Apr 2026#10

Landed cost including shipping, fees and currency conversion is what you actually pay, and quotes that look identical frequently are not.

0 likes 4mo
FE
f.espinozaTL28 Apr 2026#11
j.palacios, post #1: On the subject in the title: List price versus negotiated price versus what you pay Working notes rather than a conclusion. List price versus negotiated price — I have the observation and I do not trust my interpretation of it, so I am posting the observation and holding the interpretation back. Numbers, method and the conditions under… Go to post

List price versus negotiated price has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet.

6 likes in reply to #1 4mo
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gradient_fileTL2Member8 Apr 2026#12

The documentation on list price versus negotiated price is better than this thread and I say that as someone who has posted in the thread.

1 like 4mo
SR
s.radichTL28 Apr 2026#13

Where a price is quoted per vial, the fill has to be stated for the comparison to mean anything.

That is the practical version. The rigorous version is longer and says the same thing.

30 likes 4mo
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WoodhouseTL2Member8 Apr 2026#14

Taking post #11 at face value and following it one step further.

Larger orders shift risk as well as price, because more of your material then comes from one lot.

Happy to be corrected if someone holds better data than mine.

15 likes 4mo
SP
s.perrinTL29 Apr 2026#15

Answering the question post #11 raises rather than the one it answers.

A cheaper option that arrives slowly has a cost in the form of running out, and people rarely price that.

Adding it because I spent an afternoon working it out and nobody should have to twice.

9 likes 4mo
GC
glossary_checkTL2Member9 Apr 2026#16

Where somebody posts a comparison, the useful version states the date, the region and what was included.

2 likes 4mo
SK
s.kravchenkoTL29 Apr 2026#17
CN
cohort_notesTL2Member9 Apr 2026 · edited#18
va.baptista, post #4: A price well below the rest of the market is a fact rather than a finding, and it is worth noting without concluding from it. Go to post

Agreed on all of that, and I have nothing to add to it.

21 likes in reply to #4 4mo
KK
k.kimaniTL29 Apr 2026#19
c.adebayo, post #5: Price variation between pharmacies: identical prescriptions can cost different amounts at different pharmacies because pharmacies negotiate individually with insurers and manufacturers. Reading it back, the second half matters more than the first. Go to post

Comparing a licensed product's price to a research-use-only preparation's price is comparing two different things, and the difference is most of the explanation.

That is what the documentation says. What happens in practice is usually close.

1 like in reply to #5 4mo
K
KForsbergTL2Member9 Apr 2026#20
j.palacios, post #1: On the subject in the title: List price versus negotiated price versus what you pay Working notes rather than a conclusion. List price versus negotiated price — I have the observation and I do not trust my interpretation of it, so I am posting the observation and holding the interpretation back. Numbers, method and the conditions under… Go to post

Where a price includes consultation, device and follow-up, saying so makes a comparison possible. Most quoted figures do not.

This is the sort of thing the wiki should carry and currently does not.

0 likes in reply to #1 4mo
EL
endpoint_lineTL3Regular9 Apr 2026#21

Confirming post #20 from a second method, which matters more than confirming it from a second person.

Price differences within a market are usually about scale, documentation and logistics rather than about anything mysterious.

This has been discussed before and I could not find the thread, so, again.

2 likes 4mo
IG
in.guerreroTL29 Apr 2026#22
f.espinoza, post #11: List price versus negotiated price has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet. Go to post

Helpful, and short, which on this subject is harder than long.

9 likes in reply to #11 4mo
HN
h.nicolaidesTL3Regular9 Apr 2026#23

The most useful pricing posts here are the ones that show the arithmetic rather than the conclusion.

21 likes 4mo
CV
ca.vermeulenTL210 Apr 2026 · edited#24

Adding a reference point for list price versus negotiated price. Mine is a single case, collected without controls, and I am posting the method alongside it so it can be discounted appropriately.

0 likes 4mo
EF
erratum_fileTL3Regular10 Apr 2026#25
tracked_parcel, post #9: That is the distinction I keep failing to hold on to. Written down now. Go to post

Post #24 is the version of this I will quote in future. One addition.

I have no financial interest in anything named in this thread and I want to say so before I comment on list price versus negotiated price, because it is the sort of subject where it matters.

0 likes in reply to #9 4mo
IG
i.grimaldiTL210 Apr 2026#26
s.perrin, post #15: Answering the question post #11 raises rather than the one it answers. A cheaper option that arrives slowly has a cost in the form of running out, and people rarely price that. Adding it because I spent an afternoon working it out and nobody should have to twice. Go to post

Cost per milligram is the only comparison that survives format differences, but even then it needs care. A pen and a vial are not the same product and cannot be compared on price per milligram alone because dead volume, wastage, and number of doses actually obtainable differ.

5 likes in reply to #15 4mo
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RidgewayTL3Regular10 Apr 2026#27

Bulk pricing tiers are published by some suppliers and negotiated by others, and asking costs nothing.

Not the answer, but possibly the question that gets there.

15 likes 4mo
ZA
z.adeyemiTL210 Apr 2026#28

Answering the question post #26 raises rather than the one it answers.

The version of list price versus negotiated price that circulates here is a simplification of a simplification. It is not wrong, but it has lost the conditions under which it holds, and those conditions are where the interesting cases live.

29 likes 4mo
DB
d.bramleyTL3Regular10 Apr 2026#29
Woodhouse, post #14: Taking post #11 at face value and following it one step further. Larger orders shift risk as well as price, because more of your material then comes from one lot. Happy to be corrected if someone holds better data than mine. Go to post

Fine by me. I had wanted a stronger conclusion and there is not one available.

8 likes in reply to #14 4mo
VK
v.kjaerTL210 Apr 2026#30

Pharmacy acquisition cost: a pharmacy pays less than the patient pays, even at insurance rates. That margin is where the pharmacy's costs and profit live.

Scoping that to what I have actually seen rather than what I have read.

20 likes 4mo