Topic summary

Solubility limits and what a cloudy solution is telling you

Pharmacology › Formulation chemistry cloudy or discoloured solution storage counter-ion content

This is a generated summary. It shows the 5 most-liked posts from a topic of 16, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.

s.solbergTL223 Jan 2026 · edited#2

Antioxidants: compounds that prevent oxidation (which damages peptides) are sometimes included. Methionine oxidation is a common degradation pathway and antioxidants help prevent it.

I would rather say I do not know than round it up to an answer.

19 likes 6mo

v.salgadoTL214 Mar 2026#5

No disagreement from me. Posting only so the question does not look ignored.

27 likes 4mo

s.coelhoTL26 May 2026#9

Post #7 describes the usual case. This is about the unusual one.

Solubility limits came up in a thread eighteen months ago and was answered well. I cannot find it, which is itself the problem, so here is the reconstruction.

20 likes 3mo

t.batistaTL223 Jun 2026#13

Having read the whole solubility limits thread before replying: the question in the first post has not actually been answered yet, and three of us have answered a nearby one instead.

15 likes 1mo

bench_peakTL3Regular5 Jul 2026 · edited#14

An honest declaration on solubility limits: I have a prior here and it is strong enough that you should weight what I say downward. Stating it rather than hiding it.

30 likes 23d

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This topic was referenced in

About the Formulation chemistry categoryPharmacology › Formulation chemistry · 4 replies
[2026 update] Buffers, pH and why a formulation is a formulationPharmacology › Formulation chemistry · 2 replies

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