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Topic summary

When a preprint is the best available evidence and we say so

This is a generated summary. It shows the 9 most-liked posts from a topic of 161, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
M
microgramsTL2Regular27 Jul 2025#4
m.kjaer, post #3: The arithmetic in the opening post is right; the assumption feeding it is the part to check. Retractions and corrections do not propagate well from preprint servers. A citation that was fine when made can quietly become wrong. If it helps: the failure mode here is usually boring rather than dramatic. Go to post

Where the preprint reasoning breaks down for me is the step from the group result to the individual case. That step is almost never argued for.

31 likes in reply to #3 12mo
SC
sourced_claimsTL3Regular Solution29 Jul 2025#8

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

7 likes 12mo
BV
bias_varianceTL4Biostatistician2 Aug 2025#18
np_gilmore, post #6: Post #2 put the caveat in the right place and I want to underline it. Adding a null result on preprint. I looked, carefully, and found nothing, and null results deserve posting precisely because they never are. Go to post

The arithmetic in post #17 is right; the assumption feeding it is the part to check.

Reading a preprint properly means doing some of the reviewer's job: methods first, then whether the analysis matches the plan, then the conclusion.

This is the version I would want a new member to read first.

31 likes in reply to #6 12mo
DM
d.magalhesTL2Member11 Aug 2025#46
mira.patel, post #38: Where a preprint contradicts a published trial, the prior should favour the trial. Where it extends one, the preprint can be genuinely useful. Anyone with a larger sample, please post it. Go to post

If you cite a preprint in a maintained document here, the convention is to label it in the sentence and to note the check date. The document review will catch the update.

I would not lead a decision with this, but I would not ignore it either.

32 likes in reply to #38 12mo
CN
cannula_notesTL2Member19 Aug 2025#73

Worth separating two things that post #72 runs together.

If you cite a preprint in a maintained document here, the convention is to label it in the sentence and to note the check date. The document review will catch the update.

I am reporting what happened, not recommending it.

30 likes 11mo
VB
v.baptistaTL222 Aug 2025#85

Reading a preprint properly means doing some of the reviewer's job: methods first, then whether the analysis matches the plan, then the conclusion.

33 likes 11mo
NO
n.oseiTL228 Aug 2025#109

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

That has held every time I have looked, which is not the same as always.

31 likes 11mo
RL
r.lundgrenTL25 Sep 2025#141

Coming back to post #137, because the follow-up matters more than the original answer.

Reading a preprint properly means doing some of the reviewer's job: methods first, then whether the analysis matches the plan, then the conclusion.

I would call that likely rather than established.

30 likes 11mo
MS
m.stephanopoulosTL3Regular8 Sep 2025#155
v.szabo, post #67: Peer review catches some things reliably — missing methods, unsupported conclusions, statistical mistakes of the obvious kind — and misses others routinely. Knowing which is which makes preprint reading easier. Go to post

A preprint reporting a null result is more likely to stay a preprint, which biases the published literature and makes preprint servers more valuable rather than less.

Two people can read the same figure differently here and both be reasonable.

32 likes in reply to #67 11mo

Read the full topic (161 posts)

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