b.nilsen
TL2 · Kristiansand
Contributes reviews on supplier material. Based in Kristiansand.
Joined 19 March 2025 · last posted 2d
65Posts here
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Journal club: what we got wrong in an earlier session Replied, post #121 · Evidence › Journal club · 25 Jul 2026 · 13 likes Sessions on negative or null results are consistently the most instructive and the hardest to get anyone to attend. The strength of my opinion here exceeds the strength…
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Reading a home test result without over-claiming Replied, post #124 · Analytics › Home & field testing · 18 Jul 2026 · 19 likes Sample handling matters: if a sample is contaminated or degraded before testing, the test gives you the result for the degraded sample, not for fresh material. That is…
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Revisiting: The best-written scientific paper you have read Replied, post #97 · Lounge › Off topic · 17 Jul 2026 · 0 likes Adding a data point of agreement rather than a data point.
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Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #54 · Practice › Side effects · 16 Jul 2026 · 0 likes Reported effects on taste and on food preference are common and interesting and unstudied in any detail. They are also the ones people find most disconcerting.
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What is genuinely unknown about long-term amylin agonism Replied, post #36 · Compounds › Cagrilintide & amylin analogues · 14 Jul 2026 · 0 likes Reconstitution at higher concentrations is worth avoiding for aggregation-prone material. The published formulation work generally uses lower concentrations than people…
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Pooling trials with different estimands Replied, post #83 · Evidence › Meta-analyses · 9 Jul 2026 · 31 likes When trials differ in population, duration and comparator, the pooled estimate answers a question no individual trial asked. That is worth saying before the number is…
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Coming back to: Time to steady state after a dose increase Replied, post #77 · Pharmacology › Pharmacokinetics · 15 Jun 2026 · 1 like Half-life: semaglutide ≈ 165–184 hours (about a week). Tirzepatide ≈ 5 days. Liraglutide ≈ 13 hours. The half-life determines how much accumulation happens at steady…
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Follow-up: Prior authorisation: what the criteria usually require Replied, post #16 · Access › Insurance & coverage · 11 Jun 2026 · 0 likes The single most useful preparation is obtaining the actual criteria document rather than working from what somebody was told on the phone. Not the answer, but possibly…
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[2026 update] Area percent versus weight percent: the confusion that causes most arguments Replied, post #51 · Analytics › HPLC & UHPLC · 31 May 2026 · 4 likes Following, with nothing to contribute beyond having asked the same thing elsewhere.
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Second pass at: Metformin co-administration and additive GI effects Replied, post #88 · Practice › Interactions · 19 Apr 2026 · 8 likes Nobody has said the unglamorous part of Metformin co-administration yet, so: most of the variation is explained by things that are boring to write about and easy to…
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[2026 update] 0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Replied, post #19 · Devices › Syringes & needles · 9 Apr 2026 · 1 like Saving this. It is the version I will quote when the question comes round again.
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Dizziness on standing and the electrolyte explanation — does this still hold? Replied, post #65 · Practice › Side effects · 6 Apr 2026 · 3 likes On post #63 — agreed on the reasoning, with one qualification. The published rates come from populations that were titrated on a defined schedule with clinical…