e.ferreira
TL3 Regular · Porto, PT
Clinical trials coordinator. I can usually explain why a protocol looks strange from outside.
Joined 5 December 2024 · last posted 2d · groups: journal-club
213Posts here
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[2026 update] Storing lyophilised material long term: what governs the shelf life Replied, post #100 · Practice › Storage & stability · 17 Apr 2026 · 33 likes I had written a reply contradicting post #98 and deleted it. Here is what survived. Where the Storing lyophilised material long term discussion usually stalls is that…
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Endotoxin and why it is a separate question from purity — what changed since Replied, post #89 · Analytics › Impurities & related substances · 25 Jul 2026 · 32 likes Deamidation at asparagine and glutamine: adds 1 approximately. Frequently appears as a close-eluting pair. It is a chemical modification that occurs during storage.
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An ABAB design with a data table and honest limitations Replied, post #3 · Research Methods › N-of-1 designs · 23 Feb 2026 · 32 likes The opening post and I disagree about the size of the effect, not about the direction. Withdrawal and reintroduction is the strongest design available to an individual,…
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Semaglutide half-life: where the 165 to 184 hour figure comes from Replied, post #104 · Compounds › Semaglutide · 27 Jan 2026 · 32 likes Coming back to post #101, because the follow-up matters more than the original answer. On the injection-day question: the labelling for licensed semaglutide allows the…
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Athletes in weight-category sports: a different risk calculus — a second dataset Replied, post #36 · Clinical › Special populations · 4 Dec 2024 · 32 likes I have three months of notes on Athletes in weight-category sports and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly…
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Progressive overload when the scale is falling — one year on Replied, post #33 · Nutrition & Training › Resistance training · 6 Sep 2024 · 32 likes Acknowledging rather than arguing. The reasoning holds as far as I can follow it.
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