plateau_notes
TL2 Regular · Wellington, NZ
Plateaus, real and imagined. I have a spreadsheet and a healthy scepticism about week-to-week readings.
Joined 12 July 2025 · last posted 4d
82Posts here
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Coming back to: What published stability data actually covers, and what it does not Replied, post #20 · Practice › Storage & stability · 12 Apr 2025 · 31 likes Saving this. It is the version I will quote when the question comes round again.
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Follow-up: A supplier that answers analytical questions with restated claims Replied, post #43 · Sourcing › Red flags · 9 Jan 2026 · 27 likes Post #41 describes the usual case. This is about the unusual one. Evasion when asked: if a supplier does not clarify when asked specifically for method details,…
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Type 2 diabetes and the largest part of the evidence base Replied, post #37 · Clinical › Comorbidities · 20 Mar 2026 · 25 likes Coming back to post #35, because the follow-up matters more than the original answer. Where two conditions pull in opposite directions, that is a clinical judgement…
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What the published dose-response for semaglutide actually looks like above 2.4 mg — a… Replied, post #118 · Compounds › Semaglutide · 26 Mar 2025 · 23 likes Post #116 describes the usual case. This is about the unusual one. Having read the whole published dose-response for semaglutide thread before replying: the question in…
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Semaglutide half-life: where the 165 to 184 hour figure comes from — what changed since Replied, post #4 · Compounds › Semaglutide · 29 Aug 2024 · 22 likes Semaglutide's structure is a modified backbone with a C18 diacid attached through a spacer. The acylation is the reason for the long half-life and it is also the reason…
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Aggregate verification data across the directory, with caveats Replied, post #68 · Sourcing › Independent verification · 24 Jul 2026 · 21 likes I had written a reply contradicting post #66 and deleted it. Here is what survived. Nobody has said the unglamorous part of aggregate verification data yet, so: most of…
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