A 5 mg vial and a 0.25 mg dose: the arithmetic in full Writing it up because I had to work it out twice and would rather nobody else did.
5 mg vial: setting out the arithmetic in full, because I have had to do it twice and I would rather nobody else did.
Every step is shown. If the answer is wrong the error will be visible, which is the point of writing it out rather than posting the result.
Worth separating 5 mg vial as a question about the compound from 5 mg vial as a question about the documentation. They get answered by different people and only one of them is answerable here.
Preservative effectiveness is tested against a defined microbial challenge under defined conditions. It is not a licence to treat an entered vial as sterile indefinitely, and no supplier claims otherwise.
If this contradicts something upthread, the upthread version may well be the better one.
No notes. Posting so the count is not one.
I will take the caveat as seriously as the claim, which is the point of putting it there.
The best check on any reconstitution calculation is to do it twice by two different routes — mass per volume, then volume per dose — and see whether they agree. They should, and when they do not it is nearly always the concentration step.
Adding this to the thread rather than to the wiki, because I am not confident enough for the wiki.
Building on post #131 rather than restating it.
Taking 5 mg vial seriously for a moment rather than deflecting: the honest position is that the community has observations and no controlled comparison, and those two things support very different sentences.
If your arithmetic gives a volume smaller than one graduation on your syringe, the answer is a lower concentration rather than a more careful hand.
Read the full topic (142 posts)
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A 5 mg vial and a 0.25 mg dose: the arithmetic in full — what changed since
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Over-dilution: when your dose falls below one readable graduation
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Reconstituting a multi-strength kit without mixing yourself up
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Why I now write the concentration on the vial in marker
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Validating a calculator against hand arithmetic
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