Practical experience of fixed versus detachable needles, offered as one case with the conditions stated, not as a general finding. Conditions first, because they are what make it interpretable.
Fixed versus detachable needles: the trade-offs posts 31–60
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.
Safety-engineered needles are worth using if you have children or anyone else in the house, and the retraction mechanism occupies dead volume that ordinary syringes do not.
Post #31 describes the usual case. This is about the unusual one.
U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.
An observation about fixed versus detachable needles that I cannot explain and am posting anyway, on the principle that unexplained observations are more useful public than private.
Filter needles are for drawing from glass ampoules where particulate is a real risk. For a stoppered vial they add dead volume in exchange for very little.
Anyone with a larger sample, please post it.
Post #35 put the caveat in the right place and I want to underline it.
Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.
Building on post #39 rather than restating it.
The documentation on fixed versus detachable needles is better than this thread and I say that as someone who has posted in the thread.
Post #40 is right about the mechanism and I think understates the practical bit.
Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.
Offering a way to settle fixed versus detachable needles rather than another opinion about it. Two measurements, taken the same way, a fortnight apart. If the difference is within the noise, the question was not answerable at this precision.
The arithmetic on fixed versus detachable needles is the easy part and it is where the errors are, which is an uncomfortable combination. Show your working and someone will catch it.
Confirming post #43 from a second method, which matters more than confirming it from a second person.
Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.
I had written a reply contradicting post #42 and deleted it. Here is what survived.
U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.
Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.
I would call that likely rather than established.
Everything in post #46 holds. The case it does not cover is the one I have.
Adding what did not work for me on fixed versus detachable needles, since the failures never get written up and they are half the useful information.
Fixed versus detachable needles is well covered in the tag pages, and the older discussions are better than the recent ones because they were argued out properly. Worth twenty minutes before adding to this one.
Narrowing post #50, because the general version has more than one answer.
Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.
The step people skip is the one I have spelled out.
Needle length for subcutaneous delivery is a question about tissue depth and injection angle together. Short needles at ninety degrees and longer ones at an angle reach comparable depths.
Saving this. It is the version I will quote when the question comes round again.
Taking fixed versus detachable needles seriously for a moment rather than deflecting: the honest position is that the community has observations and no controlled comparison, and those two things support very different sentences.
The reason fixed versus detachable needles keeps being re-asked is that the answer is conditional and people quote it without the condition. It is not that the answer is unknown.
Where I part company with post #53, and it is a narrow parting.
U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.
Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.
Right — I had this wrong and I am glad to have read it before it mattered.