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Devices · Syringes & needles · continued

Fixed versus detachable needles: the trade-offs posts 91–120

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

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e.ferreiraTL3Regular4 Jan 2025#91
hana.sato, post #52: Narrowing post #50, because the general version has more than one answer. Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum. The step people skip is the one I have spelled out. Go to post

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

2 likes in reply to #52 19mo
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KAnderssonTL3Regular5 Jan 2025 · edited#92
c.amankwah, post #32: Safety-engineered needles are worth using if you have children or anyone else in the house, and the retraction mechanism occupies dead volume that ordinary syringes do not. Go to post

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

I have no interest in any supplier named above.

0 likes in reply to #32 19mo
EN
e.ndiayeTL25 Jan 2025#93

Everything in post #89 holds. The case it does not cover is the one I have.

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

The general answer and the answer for your case may diverge here.

29 likes 19mo
DS
d.szymanskiTL3Wiki editor6 Jan 2025#94

Narrowing post #93, because the general version has more than one answer.

Adding a null result on fixed versus detachable needles. I looked, carefully, and found nothing, and null results deserve posting precisely because they never are.

14 likes 19mo
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m.mwangiTL26 Jan 2025#95
e.roos, post #64: Post #60 and I disagree about the size of the effect, not about the direction. I have three months of notes on fixed versus detachable needles and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly drew the opposite conclusion from the first fortnight. Go to post

Gauge is the outside diameter and higher numbers are thinner. Thinner needles hurt less and draw more slowly, which is the entire trade.

This has been discussed before and I could not find the thread, so, again.

5 likes in reply to #64 19mo
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g.tanakaTL3Regular7 Jan 2025#96

Nothing to add on the substance. Thank you for taking the question at face value.

0 likes 19mo
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i.guerreroTL27 Jan 2025#97
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titration_diaryTL3Regular8 Jan 2025#98

Fixed versus detachable needles is worth one more sentence than it usually gets, and the sentence is the one about how the number was arrived at.

20 likes 19mo
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c.serranoTL28 Jan 2025#99
y.adebayo, post #36: My understanding of fixed versus detachable needles is a few years old and may have been superseded. If it has been, I would genuinely like to know rather than keep repeating it. Go to post

On post #98 — agreed on the reasoning, with one qualification.

U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.

The short version is the first sentence; the rest is why.

9 likes in reply to #36 19mo
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t.nardoneTL3Regular8 Jan 2025#100

Picking up post #98: that is the part I would want checked first.

I would keep fixed versus detachable needles and the decision it usually gets used for separate in this thread. They are related and they are not the same question, and merging them is why the last one went badly.

2 likes 19mo
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o.cousineauTL3Regular9 Jan 2025#101

Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.

29 likes 19mo
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k.haddadTL29 Jan 2025#102

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

Not a conclusion. A place to stand while looking for one.

14 likes 19mo
MI
m.ivaturiTL210 Jan 2025#103
n.norgaard, post #46: I had written a reply contradicting post #42 and deleted it. Here is what survived. U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre. Go to post

Post #101 put the caveat in the right place and I want to underline it.

Filter needles are for drawing from glass ampoules where particulate is a real risk. For a stoppered vial they add dead volume in exchange for very little.

I have written this out at length because the short version keeps being misread.

5 likes in reply to #46 19mo
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a.silvaTL210 Jan 2025#104

I will take the caveat as seriously as the claim, which is the point of putting it there.

0 likes 19mo
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excursion_checkTL3Regular11 Jan 2025#105

Everything in post #101 holds. The case it does not cover is the one I have.

A detachable luer needle plus hub can retain enough volume to matter. Whether it matters to you depends on your dose, and the arithmetic is worth doing once.

0 likes 19mo
SV
s.vanheckeTL211 Jan 2025#106
n.laurent, post #81: Safety-engineered needles are worth using if you have children or anyone else in the house, and the retraction mechanism occupies dead volume that ordinary syringes do not. I would put a moderate confidence on that and no more. Go to post

Safety-engineered needles are worth using if you have children or anyone else in the house, and the retraction mechanism occupies dead volume that ordinary syringes do not.

20 likes in reply to #81 19mo
CN
c.niemelTL3Regular12 Jan 2025 · edited#107
m.strand_rph, post #58: Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers. Go to post

Whatever the answer on fixed versus detachable needles turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, invite the correction.

9 likes in reply to #58 18mo
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r.mwangiTL212 Jan 2025#108

Taking post #105 at face value and following it one step further.

On fixed versus detachable needles, I would rather understate and be corrected upward than overstate and be quoted. That is a house style here and it is a good one.

2 likes 18mo
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l.chevalierTL3Regular13 Jan 2025#109

Understood. Thank you for being specific about the limits of it.

15 likes 18mo
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m.adebayoTL213 Jan 2025#110

Post #108 answers the question as asked. The question underneath it is different.

Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.

It took me longer than it should have to see that.

6 likes 18mo
AK
a.kwiatkowskiTL2Member14 Jan 2025#111

U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.

0 likes 18mo
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t.vargaTL214 Jan 2025#112
m.ivaturi, post #103: Post #101 put the caveat in the right place and I want to underline it. Filter needles are for drawing from glass ampoules where particulate is a real risk. For a stoppered vial they add dead volume in exchange for very little. I have written this out at length because the short version keeps being misread. Go to post

On fixed versus detachable needles, the part that usually goes wrong is that the question is asked as though it has one answer. It has a range, and the width of the range is the interesting bit.

If you can post the two or three numbers you are working from, several people here will check the arithmetic rather than argue about the conclusion.

1 like in reply to #103 18mo
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IRenaudinTL2Member15 Jan 2025#113
p.krastev, post #17: Needle length for subcutaneous delivery is a question about tissue depth and injection angle together. Short needles at ninety degrees and longer ones at an angle reach comparable depths. Adding it because I spent an afternoon working it out and nobody should have to twice. Go to post

Taking post #112 at face value and following it one step further.

Two claims get bundled together under fixed versus detachable needles and they need separating. The descriptive one — this is what was observed — is usually well supported. The causal one — this is why — usually is not.

Almost every disagreement in threads like this one dissolves once you say which of the two you are making.

6 likes in reply to #17 18mo
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n.kaufmannTL215 Jan 2025#114

Thank you for the correction. I would rather find out here than later.

16 likes 18mo
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crossover_entryTL3Regular15 Jan 2025#115

Coring the stopper is a real phenomenon with repeated entries at the same point and blunt needles. Varying the entry point slightly and using a fresh needle prevents it.

Where I would look next, rather than where I would stop.

0 likes 18mo
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l.lundgrenTL216 Jan 2025#116

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

That much is documented. The rest is how I have interpreted it.

3 likes 18mo
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NardoneTL2Member16 Jan 2025 · edited#117
s.karlsen_rph, post #29: This follows post #26 rather than contradicting it. Having read the whole fixed versus detachable needles thread before replying: the question in the first post has not actually been answered yet, and three of us have answered a nearby one instead. Go to post

This follows post #116 rather than contradicting it.

Fixed versus detachable needles has been discussed here with more heat than it deserves, mostly because two definitions have been in play the whole time.

10 likes in reply to #29 18mo
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l.vermeulenTL217 Jan 2025#118

Worth separating two things that post #115 runs together.

The most useful thing anyone has posted about fixed versus detachable needles in this category was a table of what had been measured and by whom. That is what I would want again.

22 likes 18mo
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g.pemberton_ukTL317 Jan 2025#119
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n.boatengTL218 Jan 2025#120
isotonic_sheet, post #16: Confirming post #13 from a second method, which matters more than confirming it from a second person. On fixed versus detachable needles the community has more anecdote than the confidence in this thread implies, and I include my own contribution in that. Go to post

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

The confident version of this sentence would be wrong, so here is the hedged one.

0 likes in reply to #16 18mo