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Contains arithmetic shown step by step.

139 topics 42 solved Group: Status

Practice 47 Research Methods 26 Start Here 25 Data & Tools 14 Pharmacology 14 Devices 13

Related in this group: solved · open question · needs a source · long read · beginner friendly · data table · disputed

139 topics · page 5 of 5

Topic	Participants	Replies	Views	Activity
Second pass at: Regression to the mean in progress reports Research Methods › Statistics effect size worked example heterogeneity Second pass at: Regression to the mean in progress reports Writing it up because I had to work it out twice and would rather nobody else did. Posting a small dataset on Regression. It is mine, it is…	+71	75	4k	17mo
Second pass at: Albumin binding and how it produces a long half-life Pharmacology › Pharmacokinetics missed dose worked example semaglutide Posting this under the heading it deserves: Second pass at: Albumin binding and how it produces a long half-life Everything below is what sits behind that. A narrow question about Albumin binding,…	+7	11	31k	17mo
Feature request: should a dose-equivalence tool exist at all? Data & Tools › Calculators site feedback worked example concentration maths syringe units Closed Feature request: should a dose-equivalence tool exist at all? — that is the question, and I have not found it answered plainly anywhere I have looked. Reading back through what has been written here about…	+21	25	4.8k	18mo
Second pass at: Multiplicity when you track fifteen variables Research Methods › Statistics number needed to treat confounding effect size worked example Posting this under the heading it deserves: Second pass at: Multiplicity when you track fifteen variables Everything below is what sits behind that. Two things I would like separated before anyone answers on…		2	12k	18mo
Revisiting: Holding a dose indefinitely: is there a documented downside? Practice › Dosing & titration titration tirzepatide worked example missed dose Solved The question in the title: Revisiting: Holding a dose indefinitely: is there a documented downside? I will give what I have already checked below so nobody repeats it. I have read the maintained page on this…	+26	30	4.5k	18mo
Escalating every six weeks instead of four: what I observed over eight months Practice › Dosing & titration titration worked example dose reduction Escalating every six weeks instead of four: what I observed over eight months Writing it up because I had to work it out twice and would rather nobody else did. Asking about escalating every six weeks instead…	+27	31	432	18mo
Sample size intuition for a personal experiment Research Methods › Statistics number needed to treat heterogeneity confounding effect size On the subject in the title: Sample size intuition for a personal experiment Working notes rather than a conclusion. A follow-up question about sample size intuition that I did not know to ask the first time.…		4	62k	18mo
Fixed versus detachable needles: the trade-offs Devices › Syringes & needles dead volume subcutaneous injection syringe units worked example Solved Posting this under the heading it deserves: Fixed versus detachable needles: the trade-offs Everything below is what sits behind that. I was wrong about fixed versus detachable needles in a thread last spring…	+117	121	7.3k	18mo
Follow-up: Dead volume across syringe and needle combinations Devices › Syringes & needles syringe units worked example subcutaneous injection dead volume Solved Dead volume across syringe and needle combinations — setting out what I have, and where I think it stops being reliable. A follow-up question about Dead volume across syringe that I did not know to ask the…	+81	98	22k	18mo
Follow-up: Where the four-week escalation interval comes from, and what it is not Practice › Dosing & titration tirzepatide dose reduction worked example missed dose Wiki Where the four-week escalation interval comes from, and what it is not Writing it up because I had to work it out twice and would rather nobody else did. A follow-up question about four-week escalation…	+131	147	47k	18mo
Second pass at: Choosing a concentration on purpose rather than by accident Practice › Reconstitution worked example dead volume reconstitution Second pass at: Choosing a concentration on purpose rather than by accident Writing it up because I had to work it out twice and would rather nobody else did. Posting a small dataset on Choosing a…	+44	48	1k	19mo
Why "any advice?" is the least effective ending for a post Start Here › How to Ask worked example guidelines site feedback beginner friendly The question in the title: Why "any advice?" is the least effective ending for a post I will give what I have already checked below so nobody repeats it. Counting it rather than describing it, because the…	+113	126	55k	20mo
Washout with a one-week half-life: the arithmetic Research Methods › N-of-1 designs effect size data table worked example Wiki Washout with a one-week half-life: the arithmetic — setting out what I have, and where I think it stops being reliable. Washout: setting out the arithmetic in full, because I have had to do it twice and I…	+90	96	44k	20mo
Follow-up: Escalating every six weeks instead of four: what I observed over eight months Practice › Dosing & titration titration worked example tirzepatide dose reduction Escalating every six weeks instead of four: what I observed over eight months — setting out what I have, and where I think it stops being reliable. Two things I would like separated before anyone answers on…		4	164	20mo
Revisiting: Five questions in one post gets you one answer — how to split them Start Here › How to Ask worked example guidelines beginner friendly site feedback Solved Revisiting: Five questions in one post gets you one answer — how to split them Writing it up because I had to work it out twice and would rather nobody else did. Working notes on Five questions rather than a…	+2	6	13k	20mo
Time to steady state after a dose increase Pharmacology › Pharmacokinetics tirzepatide liraglutide worked example missed dose On the subject in the title: Time to steady state after a dose increase Working notes rather than a conclusion. Working through the kinetics rather than the pharmacology, because I think the confusion here is…	+151	163	9.7k	21mo
Correlation in a self-tracked dataset: what it can support Research Methods › Statistics effect size heterogeneity worked example number needed to treat Closed Correlation in a self-tracked dataset: what it can support — setting out what I have, and where I think it stops being reliable. Posting a small dataset on correlation. It is mine, it is uncontrolled, and the…	+152	166	48k	23mo
The mass-error checker and its intended scope Data & Tools › Calculators worked example concentration maths syringe units site feedback The mass-error checker and its intended scope Writing it up because I had to work it out twice and would rather nobody else did. Proposing that mass-error checker deserves a maintained page rather than a…	+149	167	42k	2y
Where the four-week escalation interval comes from, and what it is not Practice › Dosing & titration missed dose semaglutide tirzepatide titration Solved On the subject in the title: Where the four-week escalation interval comes from, and what it is not Working notes rather than a conclusion. Working notes on four-week escalation interval rather than a…	+56	60	21k	2y