Ranked by engagement

Top topics — this quarter page 9

Ranked by replies, likes and views over this quarter, with a bonus for topics that reached a marked solution. Engagement is a proxy for usefulness and a poor one; the documentation commons is the better index of what is settled.

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515 topics · page 9 of 14

Topic	Participants	Replies	Views	Activity
Follow-up: Signs of dehydration worth acting on Safety › Adverse events delayed gastric emptying pancreatitis hypoglycaemia Posting this under the heading it deserves: Signs of dehydration worth acting on Everything below is what sits behind that. A follow-up question about Signs of dehydration worth acting that I did not know to…	+35	39	9.8k	1d
Second pass at: Programming during a large energy deficit Nutrition & Training › Resistance training DXA lean mass loss fatigue Posting this under the heading it deserves: Second pass at: Programming during a large energy deficit Everything below is what sits behind that. Two things I would like separated before anyone answers on…	+44	48	632	30d
Second pass at: The storage lookup and where its data comes from Data & Tools › Calculators concentration maths syringe units site feedback worked example On the subject in the title: Second pass at: The storage lookup and where its data comes from Working notes rather than a conclusion. Two things I would like separated before anyone answers on storage lookup,…	+38	42	13k	19d
Racemisation and why it is invisible to a mass measurement — what changed since Analytics › Impurities & related substances forced degradation water content counter-ion content Racemisation and why it is invisible to a mass measurement — what changed since Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of…	+11	15	42k	16d
Residual solvents and scavengers: what is looked for — what changed since Analytics › Impurities & related substances forced degradation water content data table HPLC Solved Residual solvents and scavengers: what is looked for — what changed since — setting out what I have, and where I think it stops being reliable. What changes if the standard account of Residual solvents and…	+37	41	7k	2mo
When a dose reduction is the correct response to a side effect — a second dataset Practice › Dosing & titration worked example dose reduction titration tirzepatide When a dose reduction is the correct response to a side effect — a second dataset I have a specific reason for asking rather than idle curiosity, and the context is below. Posting a small dataset on dose…	+10	14	42k	2mo
Immortal time bias in a claims-database study — one year on Evidence › Study critique effect size risk of bias confounding Solved Posting this under the heading it deserves: Immortal time bias in a claims-database study — one year on Everything below is what sits behind that. I would like to disagree carefully with the settled view on…	+41	46	3.7k	22h
Publication patterns in the BPC-157 literature, examined Compounds › Repair & healing peptides preprint BPC-157 TB-500 needs a source Solved Posting this under the heading it deserves: Publication patterns in the BPC-157 literature, examined Everything below is what sits behind that. Putting the numbers in the first post, because a question about…	+40	45	3.4k	21h
Mood changes: monitoring, and when to involve a professional — what changed since Wellbeing › Mental health beginner friendly disordered eating mood Solved Mood changes: monitoring, and when to involve a professional — what changed since Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of…	+6	10	45k	25d
About the Impurities & related substances category Analytics › Impurities & related substances forced degradation counter-ion content water content Pinned Wiki Deletion sequences, oxidation, deamidation, aggregates, residual solvents, and counter-ion content. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded…	+6	10	50k	15h
How shortages have affected compounding permissions — does this still hold? Access › Shortages compounding shortage formulary FDA Solved How shortages have affected compounding permissions — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. Asking about shortages directly, because I…	+27	31	21k	17h
Reconstituting a multi-strength kit without mixing yourself up — what changed since Practice › Reconstitution concentration maths syringe units bacteriostatic water On the subject in the title: Reconstituting a multi-strength kit without mixing yourself up — what changed since Working notes rather than a conclusion. What changes if the standard account of Reconstituting…	+42	46	1k	7h
Athletes in weight-category sports: a different risk calculus Clinical › Special populations older adults adolescents disordered eating chronic kidney disease Solved Athletes in weight-category sports: a different risk calculus — setting out what I have, and where I think it stops being reliable. Something about athletes in weight-category sports does not reconcile and I…	+38	42	6.6k	1d
Splitting an overlong document into two Documentation › Wiki requests promoted to docs review date wiki post Posting this under the heading it deserves: Splitting an overlong document into two Everything below is what sits behind that. Trying to work out what would count as evidence on splitting an overlong…	+30	34	6.2k	1d
Reused chromatograms across lots: how to spot it — what changed since Analytics › COA interpretation batch & lot numbers amino acid analysis reference standards documentation quality Solved Reused chromatograms across lots: how to spot it — what changed since — setting out what I have, and where I think it stops being reliable. What changes if the standard account of Reused chromatograms across…	+34	39	20k	2mo
[2026 update] What a good consultation looks like from the other side Clinical › Prescriber conversations beginner friendly type 2 diabetes telehealth The question in the title: What a good consultation looks like from the other side I will give what I have already checked below so nobody repeats it. Good consultation: what I expected, what I found, and the…	+32	36	13k	1mo
Revisiting: The arithmetic of an intermediate dose between two label steps Practice › Dosing & titration titration worked example dose reduction tirzepatide Revisiting: The arithmetic of an intermediate dose between two label steps Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on this and I…	+41	45	808	2mo
Revisiting: Mobile reading experience on long topics Meta › Site feedback moderation guidelines site feedback Solved Posting this under the heading it deserves: Revisiting: Mobile reading experience on long topics Everything below is what sits behind that. Bringing the figures rather than the impression, since a process…	+10	15	34k	10h
When a dose reduction is the correct response to a side effect Practice › Dosing & titration dose reduction tirzepatide titration missed dose Solved When a dose reduction is the correct response to a side effect — that is the question, and I have not found it answered plainly anywhere I have looked. I have read the maintained page on this and I still have…	+38	42	2.7k	19h
Cold solution and stinging: the simplest fix Practice › Administration injection site rotation subcutaneous injection missed dose Posting this under the heading it deserves: Cold solution and stinging: the simplest fix Everything below is what sits behind that. An honest uncertainty about cold solution and stinging rather than a…	+35	39	8.2k	30d
Clearance pathways and what renal impairment changes Pharmacology › Pharmacokinetics missed dose liraglutide tirzepatide worked example Clearance pathways and what renal impairment changes Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of clearance pathways is wrong? I…	+11	15	43k	2mo
PIONEER 6 cardiovascular safety, read as a safety trial rather than an efficacy one Compounds › Oral incretins PIONEER programme SOUL trial randomised trial orforglipron Solved PIONEER 6 cardiovascular safety, read as a safety trial rather than an efficacy one — setting out what I have, and where I think it stops being reliable. Posting a small dataset on PIONEER 6 cardiovascular…	+25	29	22k	1d
Fixed versus detachable needles: the trade-offs — does this still hold? Devices › Syringes & needles syringe units needle gauge & length dead volume subcutaneous injection Solved Fixed versus detachable needles: the trade-offs — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Working notes on Fixed versus detachable…	+8	12	39k	15h
Transit times by route, from a logged dataset Sourcing › Logistics packaging customs shipping Solved Transit times by route, from a logged dataset Writing it up because I had to work it out twice and would rather nobody else did. Posting a small dataset on transit times. It is mine, it is uncontrolled, and…	+34	38	3.6k	18h
Coming back to: What the published dose-response for semaglutide actually looks like above 2.4 mg Compounds › Semaglutide effect size type 2 diabetes semaglutide STEP programme Solved The question in the title: What the published dose-response for semaglutide actually looks like above 2.4 mg I will give what I have already checked below so nobody repeats it. I would like to know what…	+23	27	9.9k	1mo
Coming back to: Telehealth prescribing models in the US Regional › North America telehealth FDA compounding insurance Posting this under the heading it deserves: Telehealth prescribing models in the US Everything below is what sits behind that. Telehealth prescribing models — I have the observation and I do not trust my…	+26	30	17k	17h
Journal club: SELECT, absolute risk, and how it was reported Evidence › Journal club journal club estimand randomised trial effect size Journal club: SELECT, absolute risk, and how it was reported Writing it up because I had to work it out twice and would rather nobody else did. A question about what the numbers mean rather than what they…		2	52k	1mo
A parcel stationary at a customs facility for nine days — does this still hold? Sourcing › Logistics temperature excursion packaging cold chain customs Solved The question in the title: A parcel stationary at a customs facility for nine days — does this still hold? I will give what I have already checked below so nobody repeats it. A logistics question, since the…	+23	27	12k	1mo
Reimbursement variation across member states Regional › European Union EMA personal import cost per milligram Reimbursement variation across member states Writing it up because I had to work it out twice and would rather nobody else did. Asking about reimbursement variation across member states directly, because I…	+7	11	39k	3mo
Follow-up: The most useful thing you learned here that was not the answer you came for Lounge › Off topic beginner friendly long read On the subject in the title: The most useful thing you learned here that was not the answer you came for Working notes rather than a conclusion. A digression I have been saving for the right category. It is…	+30	34	9.7k	11h