Ranked by engagement

Top topics — this month page 10

Ranked by replies, likes and views over this month, with a bonus for topics that reached a marked solution. Engagement is a proxy for usefulness and a poor one; the documentation commons is the better index of what is settled.

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374 topics · page 10 of 13

Topic	Participants	Replies	Views	Activity
Coming back to: Batch date after test date, and other internal inconsistencies Analytics › COA interpretation reference standards amino acid analysis documentation quality certificate of analysis On the subject in the title: Batch date after test date, and other internal inconsistencies Working notes rather than a conclusion. Batch date — I have the observation and I do not trust my interpretation of…	+21	27	420	3h
HbA1c lag and what it can and cannot tell you at eight weeks — one year on Clinical › Bloodwork liver enzymes lipase & amylase lipid panel thyroid function Posting this under the heading it deserves: HbA1c lag and what it can and cannot tell you at eight weeks — one year on Everything below is what sits behind that. A methods question rather than a substantive…	+18	22	655	13h
Semaglutide and alcohol: what is actually documented Compounds › Semaglutide STEP programme randomised trial type 2 diabetes SELECT trial Posting this under the heading it deserves: Semaglutide and alcohol: what is actually documented Everything below is what sits behind that. I would like to know what people here actually do about semaglutide…	+14	18	10k	2d
Tracking semaglutide's approved indications across jurisdictions, dated Compounds › Semaglutide semaglutide effect size SELECT trial Tracking semaglutide's approved indications across jurisdictions, dated Writing it up because I had to work it out twice and would rather nobody else did. Putting the numbers in the first post, because a…	+15	19	2.8k	1d
When a network meta-analysis is defensible and when it is not Evidence › Meta-analyses effect size heterogeneity publication bias Solved When a network meta-analysis is defensible and when it is not I have a specific reason for asking rather than idle curiosity, and the context is below. Network meta-analysis, from the point of view of someone…		2	27k	4h
Why the cheapest option is often not the cheapest Access › Pricing compounding formulary cost per milligram data table Solved Wiki Why the cheapest option is often not the cheapest I have a specific reason for asking rather than idle curiosity, and the context is below. Cheapest option: setting out the arithmetic in full, because I have…	+19	23	1.2k	12h
Language barriers in accessing a prescription abroad Access › International personal import telehealth EMA Solved Language barriers in accessing a prescription abroad Writing it up because I had to work it out twice and would rather nobody else did. I was wrong about language barriers in accessing in a thread last spring…		2	22k	1h
Second pass at: Leak-back after withdrawal and whether you lost a meaningful dose Practice › Administration subcutaneous injection needle gauge & length missed dose Second pass at: Leak-back after withdrawal and whether you lost a meaningful dose — setting out what I have, and where I think it stops being reliable. I have read the maintained page on this and I still have…	+18	22	2k	25d
The five documentation pages worth reading before you post anything — a second dataset Start Here › Welcome beginner friendly trust levels guidelines onboarding Solved On the subject in the title: The five documentation pages worth reading before you post anything — a second dataset Working notes rather than a conclusion. Posting a small dataset on five documentation pages.…		2	24k	1d
Reading a syringe in poor light, and how to avoid needing to Devices › Syringes & needles syringe units dead volume needle gauge & length worked example Solved Reading a syringe in poor light, and how to avoid needing to Writing it up because I had to work it out twice and would rather nobody else did. The question about reading a syringe that I actually want…		2	22k	just now
What other technical communities get right that we do not Lounge › Off topic beginner friendly long read Wiki What other technical communities get right that we do not — that is the question, and I have not found it answered plainly anywhere I have looked. A digression I have been saving for the right category. It is…	+2	6	23k	5h
Coming back to: Why our vendor pages link the storefront and mark it sponsored Sourcing › Vendor reports third-party testing batch & lot numbers certificate of analysis documentation quality Why our vendor pages link the storefront and mark it sponsored I have a specific reason for asking rather than idle curiosity, and the context is below. Reading back through what has been written here about…		2	22k	8h
Heart failure with preserved ejection fraction: symptom endpoints Clinical › Comorbidities type 2 diabetes obstructive sleep apnoea MASH / hepatic steatosis blood pressure Heart failure with preserved ejection fraction: symptom endpoints — setting out what I have, and where I think it stops being reliable. Heart failure with preserved ejection keeps being re-asked here and I…	+19	23	311	12d
Journal club: STEP 3 and the intensive behavioural therapy floor Evidence › Journal club randomised trial journal club effect size risk of bias Posting this under the heading it deserves: Journal club: STEP 3 and the intensive behavioural therapy floor Everything below is what sits behind that. Two things I would like separated before anyone answers…	+6	10	13k	28d
Fibre intake when total intake falls, and the constipation link — one year on Nutrition & Training › Protein & intake micronutrients lean mass loss fatigue Posting this under the heading it deserves: Fibre intake when total intake falls, and the constipation link — one year on Everything below is what sits behind that. An honest uncertainty about Fibre intake…	+9	13	16k	16h
Subgroup analyses: pre-specified versus discovered Evidence › Trials randomised trial intention to treat surrogate endpoints estimand Subgroup analyses: pre-specified versus discovered — setting out what I have, and where I think it stops being reliable. I would like to disagree carefully with the settled view on subgroup analyses, and I…		2	27k	1d
Evidence quality in the secretagogue literature: an honest assessment Compounds › Secretagogues & GH axis ipamorelin observational data GHRP class tesamorelin Solved Evidence quality in the secretagogue literature: an honest assessment Writing it up because I had to work it out twice and would rather nobody else did. I have spent a fortnight trying to pin evidence quality…		2	25k	9d
Reference intervals: how they are constructed and why one in twenty flags — does this still hold? Clinical › Bloodwork thyroid function liver enzymes lipid panel HbA1c Solved Asking directly, because I could not find a straight answer: Reference intervals: how they are constructed and why one in twenty flags — does this still hold? A methods question rather than a substantive one,…	+18	22	281	2h
About the N-of-1 designs category Research Methods › N-of-1 designs worked example confounding effect size Pinned Wiki Designing a personal experiment that could actually change your mind, including washouts and blinding. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is…		4	22k	14h
What to include when your question involves a laboratory result Start Here › How to Ask beginner friendly site feedback guidelines Asking directly, because I could not find a straight answer: What to include when your question involves a laboratory result Question in the title. Context below, and I have tried to include the things people…	+8	12	14k	2d
Is "synergy" the right word for the combination data? Compounds › Cagrilintide & amylin analogues randomised trial cagrilintide effect size Is "synergy" the right word for the combination data? — that is the question, and I have not found it answered plainly anywhere I have looked. Setting out what I think I know about this compound and asking…	+5	9	13k	25d
A comparison of home results against a laboratory result on the same vial — does this still hold? Analytics › Home & field testing ELISA third-party testing LOD & LOQ documentation quality Solved A comparison of home results against a laboratory result on the same vial — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Comparison of home…	+2	6	15k	11h
About the Reconstitution category Practice › Reconstitution reconstitution concentration maths syringe units Pinned Wiki Diluent choice, volumes, resulting concentrations, worked examples, and the errors we see most often. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is…	+1	5	15k	16h
Follow-up: External review after an internal denial Access › Insurance & coverage prior authorisation formulary insurance Solved Posting this under the heading it deserves: External review after an internal denial Everything below is what sits behind that. Proposing that External review deserves a maintained page rather than a…	+6	10	12k	15h
When your prescriber and the evidence disagree Clinical › Prescriber conversations prior authorisation telehealth type 2 diabetes When your prescriber and the evidence disagree — that is the question, and I have not found it answered plainly anywhere I have looked. What changes if the standard account of prescriber is wrong? I ask…	+14	18	273	2d
Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes Devices › Pens & autoinjectors dead volume missed dose storage subcutaneous injection Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes Writing it up because I had to work it out twice and would rather nobody else did. Question about a metering device rather…		2	18k	6h
Sleep apnoea improving and the equipment implications Wellbeing › Sleep obstructive sleep apnoea heart rate fatigue Sleep apnoea improving and the equipment implications Writing it up because I had to work it out twice and would rather nobody else did. A sleep question with what I actually recorded rather than how I feel…	+14	18	1.1k	17h
Distinguishing a red flag from an inconvenience — a second dataset Sourcing › Red flags moderation documentation quality disputed On the subject in the title: Distinguishing a red flag from an inconvenience — a second dataset Working notes rather than a conclusion. Posting a small dataset on Distinguishing a red flag. It is mine, it is…	+8	12	9.6k	1d
Repeatability versus intermediate precision — what changed since Analytics › Method validation recovery precision & repeatability linearity system suitability Posting this under the heading it deserves: Repeatability versus intermediate precision — what changed since Everything below is what sits behind that. What changes if the standard account of Repeatability…		4	21k	5h
Why side effects reset at each escalation and that is not a failure Practice › Side effects constipation nausea fatigue delayed gastric emptying Solved Why side effects reset at each escalation and that is not a failure — that is the question, and I have not found it answered plainly anywhere I have looked. The question about side effects that I actually…	+3	7	11k	14h