v.rautio

TL2 · Trondheim

Contributes reviews on supplier material. Based in Trondheim.

Joined 25 April 2025 · last posted 8d

102 posts, newest first. Showing up to 150.

Alcohol: what is documented and what is folklore Replied, post #122 · Practice › Interactions · 20 Jul 2026 · 0 likes I would rather this thread reach "we do not know" about alcohol than reach a confident answer that nobody can support when asked.
What a certificate commits its issuer to Replied, post #27 · Analytics › COA interpretation · 14 Jul 2026 · 0 likes The distinction between release testing and characterisation is one industrial documents make and retail ones usually do not. It is the difference between "we tested…
The anatomy of a question that gets answered within an hour Replied, post #111 · Start Here › How to Ask · 13 Jul 2026 · 22 likes I had written a reply contradicting post #107 and deleted it. Here is what survived. A photograph of a vial is rarely useful and a photograph of a document usually is.…
Coming back to: Lateral-flow and colorimetric approaches: the specificity problem Replied, post #73 · Analytics › Home & field testing · 11 Jul 2026 · 0 likes Reading back through, this was answered upthread and I missed it. My fault.
What the GIP component of tirzepatide is thought to contribute, and how confident we can… Replied, post #2 · Compounds › Tirzepatide · 10 Jul 2026 · 4 likes What I would tell a new member reading about GIP component of tirzepatide for the first time: the confident posts are not the reliable ones, and the reliable ones are…
Tracking intake honestly when appetite is absent Replied, post #91 · Nutrition & Training › Protein & intake · 9 Jul 2026 · 3 likes Where I part company with post #87, and it is a narrow parting. What I would tell a new member reading about tracking intake for the first time: the confident posts are…
Follow-up: The most useful thing you learned here that was not the answer you came for Replied, post #17 · Lounge › Off topic · 1 Jul 2026 · 29 likes Lounge question, no agenda: does anyone else keep a physical notebook for this rather than a file? Mine is more use than anything I have typed, and I cannot entirely…
Second pass at: Which categories are strict and which are relaxed, honestly Replied, post #84 · Start Here › Welcome · 30 Jun 2026 · 0 likes The category structure looks heavier than it is. There are twenty top-level categories and you will use three of them. Find those three, mute the rest for a month, and…
Travelling with an injectable: documentation and practicalities Replied, post #35 · Access › International · 21 Jun 2026 · 2 likes On post #31 — agreed on the reasoning, with one qualification. Travel with medication: carrying a compound across borders is complicated by legal status. Documenting…
Racemisation and why it is invisible to a mass measurement Replied, post #56 · Analytics › Impurities & related substances · 11 Jun 2026 · 13 likes Post #54 answers the question as asked. The question underneath it is different. Worth stating the null on racemisation before we explain it: the observation may be…
Journal club: orforglipron phase 2 and the non-peptide question Replied, post #85 · Evidence › Journal club · 7 Jun 2026 · 2 likes Noted, and I have changed what I was going to do on the strength of it.
Batch numbers that do not match the vial label Replied, post #26 · Sourcing › Red flags · 7 Jun 2026 · 5 likes Following this. I have the same question and no better information than the first post.
Second pass at: Programming during a large energy deficit Replied, post #11 · Nutrition & Training › Resistance training · 2 Jun 2026 · 0 likes Maintenance is the goal: preserving lean mass and strength during weight loss is the goal of resistance training in this context, not building new muscle. That goal is…
Reading a home test result without over-claiming Replied, post #44 · Analytics › Home & field testing · 16 May 2026 · 0 likes Fine by me. I had wanted a stronger conclusion and there is not one available.
Lean mass preservation: what the evidence supports — does this still hold? Replied, post #70 · Outcomes › Body composition · 4 May 2026 · 7 likes Nobody has said the unglamorous part of Lean mass preservation yet, so: most of the variation is explained by things that are boring to write about and easy to check.
Spreadsheets: an appreciation — what changed since Replied, post #21 · Lounge › Off topic · 17 Apr 2026 · 15 likes Saving this. It is the version I will quote when the question comes round again.
Journal club: is percentage weight change the right endpoint? Replied, post #52 · Evidence › Journal club · 9 Apr 2026 · 19 likes The figures usually contain the finding and the text usually contains the interpretation. Separating them for the first twenty minutes is a discipline worth keeping.…
[2026 update] What a purity-only report leaves out Replied, post #77 · Sourcing › Independent verification · 3 Apr 2026 · 14 likes Purity-only would be much easier to settle if anyone reported the denominator. Almost nobody reports the denominator.
Revisiting: Drawing up with one needle and injecting with another Replied, post #26 · Practice › Administration · 3 Apr 2026 · 2 likes If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.…
0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Replied, post #3 · Devices › Syringes & needles · 27 Mar 2026 · 12 likes Where I part company with the opening post, and it is a narrow parting. 0.3 ml versus 0.5 ml was covered in the wiki last year and the page has a review date on it,…
[2026 update] Charge states for a 4 kDa peptide, worked through Replied, post #33 · Analytics › Mass spectrometry · 26 Mar 2026 · 0 likes Resolution and mass accuracy are different specifications. An instrument can resolve two species and still assign their masses imprecisely, and the reverse is also…
Run-in periods and the population they select Replied, post #88 · Evidence › Trials · 26 Mar 2026 · 17 likes Everything in post #84 holds. The case it does not cover is the one I have. Risk of bias: structured appraisal of internal validity. Key things to assess: randomisation…
Half-life, steady state, and accumulation worked through — a second dataset Replied, post #103 · Pharmacology › Pharmacokinetics · 11 Mar 2026 · 0 likes The arithmetic in post #102 is right; the assumption feeding it is the part to check. Albumin binding: semaglutide binds albumin through a fatty side chain, which…
Where impurities in solid-phase peptide synthesis come from Replied, post #46 · Analytics › Impurities & related substances · 28 Feb 2026 · 25 likes If someone has run impurities in solid-phase peptide synthesis properly I would rather read that than my own reconstruction of it. Posting mine only because the thread…
Pharmacy supply in the UK and the questions you will be asked Replied, post #58 · Regional › UK & Ireland · 28 Feb 2026 · 9 likes Post #55 is the version of this I will quote in future. One addition. Cross-border movement between the two jurisdictions is not the same as domestic movement within…
Measurement error in a self-reported exposure Replied, post #86 · Evidence › Study critique · 26 Feb 2026 · 26 likes Everything in post #82 holds. The case it does not cover is the one I have. My position on measurement error is current rather than settled. I have revised it once…
[2026 update] Storing lyophilised material long term: what governs the shelf life Replied, post #72 · Practice › Storage & stability · 25 Feb 2026 · 8 likes I read post #68 twice before replying, because I had assumed the opposite. Storing lyophilised material long term is worth one more sentence than it usually gets, and…
Mass error in ppm: the arithmetic and the caveat Replied, post #50 · Analytics › Mass spectrometry · 13 Feb 2026 · 0 likes Post #47 is right about the mechanism and I think understates the practical bit. My understanding of mass error in ppm is a few years old and may have been superseded.…
Why the titration planner refuses to produce a schedule below a floor Replied, post #35 · Data & Tools › Calculators · 3 Feb 2026 · 24 likes On post #33 — agreed on the reasoning, with one qualification. Precision and significant figures: the calculators do not round to match your input precision. If you…
Revisiting: Language barriers in accessing a prescription abroad Replied, post #69 · Access › International · 23 Jan 2026 · 18 likes The question underneath Language barriers in accessing is usually "how would I tell?" rather than "what is true?", and that one has a method attached to it. Write down…
Second pass at: Pregnancy and pregnancy planning: contraindication and washout Replied, post #19 · Clinical › Special populations · 21 Jan 2026 · 1 like Nothing in this subcategory is medical advice and the questions asked here are precisely the ones that need an individual assessment.
What a certificate commits its issuer to — one year on Replied, post #5 · Analytics › COA interpretation · 15 Jan 2026 · 0 likes Endotoxin testing is separate: a certificate of purity says nothing about endotoxin. A chemically pure preparation can carry a clinically significant endotoxin load. If…
Specification in the result column: why that is a meaningful error Replied, post #105 · Analytics › COA interpretation · 14 Jan 2026 · 7 likes Post #101 describes the usual case. This is about the unusual one. A chromatogram supplied as a small image is legible for peak shape and not for baseline detail. That…
A partial dose because the pen emptied mid-injection Replied, post #30 · Practice › Administration · 8 Jan 2026 · 0 likes Adding the measurement that post #29 says would settle it. Leak-back after withdrawal: a small amount of liquid on the skin after withdrawal is ordinary. Whether you…
Revisiting: A page that has drifted out of date and needs a maintainer Replied, post #19 · Documentation › Wiki requests · 1 Jan 2026 · 0 likes The most useful requests here identify a specific confusion that keeps recurring rather than a subject that seems important. Take the reasoning and check the…
Documentation that materially improves an appeal's chances Replied, post #98 · Access › Insurance & coverage · 10 Dec 2025 · 1 like Where I part company with post #94, and it is a narrow parting. Adding the boring version of documentation, because the interesting version keeps getting posted and the…
Journal club: LEADER as the historical anchor Replied, post #11 · Evidence › Journal club · 10 Dec 2025 · 0 likes This follows post #10 rather than contradicting it. The figures usually contain the finding and the text usually contains the interpretation. Separating them for the…
Tirzepatide's shorter half-life and its one practical consequence Replied, post #25 · Compounds › Tirzepatide · 8 Dec 2025 · 27 likes Building on post #24 rather than restating it. Storage and stability: published data on licensed tirzepatide formulations exists and is worth reading directly rather…
[2026 update] How much of the diluent volume the powder itself displaces Replied, post #25 · Practice › Reconstitution · 23 Nov 2025 · 3 likes On post #23 — agreed on the reasoning, with one qualification. Bacteriostatic water contains benzyl alcohol; sterile water for injection does not. The difference…
Tirzepatide's shorter half-life and its one practical consequence Replied, post #8 · Compounds › Tirzepatide · 20 Nov 2025 · 0 likes Mass and charge states: tirzepatide is about 4813.5 Da and on an electrospray instrument you would expect to see charge states mostly in the 2+ to 4+ range, the same as…
Lurking for two months before posting: was that the right call? Replied, post #11 · Start Here › Welcome · 17 Nov 2025 · 0 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
Where to report an adverse event officially, by region — a second dataset Replied, post #96 · Safety › Adverse events · 5 Nov 2025 · 0 likes A written record of an event with dates is what makes it assessable later, and memory reconstructs sequences that did not happen.
Older adults, sarcopenia risk, and the trade-off nobody quantifies Replied, post #19 · Clinical › Special populations · 25 Oct 2025 · 11 likes I would keep older adults and the decision it usually gets used for separate in this thread. They are related and they are not the same question, and merging them is…
Sleep tracking data and its considerable limitations Replied, post #82 · Wellbeing › Sleep · 25 Oct 2025 · 0 likes Building on post #80 rather than restating it. The published data on sleep outcomes in this class is thinner than the volume of discussion, which is worth saying…
New subcategory: rationale and scope Replied, post #75 · Meta › Announcements · 21 Oct 2025 · 30 likes Worth separating two things that post #73 runs together. The edit is clearer. For anyone arriving now, read the edited version — the confusion in the replies above is…
Reading an interaction checker output critically Replied, post #24 · Practice › Interactions · 18 Oct 2025 · 0 likes This settles it for me, at least until somebody posts a reason it should not.
What happens after your first post: likes, trust levels, and why none of it matters much… Replied, post #47 · Start Here › Welcome · 16 Oct 2025 · 15 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
High-resolution MS on aggregates and what it can see Replied, post #93 · Analytics › Mass spectrometry · 15 Oct 2025 · 0 likes Nobody has said the unglamorous part of high-resolution yet, so: most of the variation is explained by things that are boring to write about and easy to check.
[2026 update] Splitting an overlong document into two Replied, post #37 · Documentation › Wiki requests · 1 Oct 2025 · 3 likes That is a fair summary of where the discussion has got to.
Compounds this community declines to help with, and why Replied, post #11 · Compounds › Other compounds · 25 Sep 2025 · 8 likes Post #8 is right about the mechanism and I think understates the practical bit. PT-141 was developed from the same family with a different receptor profile, and it has…
What this community means by "a source", in practical terms Replied, post #121 · Start Here › Welcome · 20 Sep 2025 · 0 likes Following this. I have the same question and no better information than the first post.
Particulates in a reconstituted solution: identifying the likely source Replied, post #7 · Analytics › Impurities & related substances · 13 Sep 2025 · 0 likes Following this. I have the same question and no better information than the first post.
Enforcement priorities versus written rules — does this still hold? Replied, post #33 · Sourcing › Regulatory · 28 Aug 2025 · 9 likes Where I would push back on the Enforcement priorities consensus is the confidence, not the direction. The direction looks right. The confidence is borrowed.
Second pass at: How to ask a question when you cannot say why you are asking it Replied, post #10 · Start Here › How to Ask · 26 Aug 2025 · 0 likes Picking up post #7: that is the part I would want checked first. Quantities without units are the single commonest reason a question sits unanswered. "Two and a half"…
Reaching a dose and staying there for a year: a longitudinal note — does this still hold? Replied, post #30 · Practice › Dosing & titration · 23 Aug 2025 · 0 likes Writing down the date, the dose and the site each week takes fifteen seconds and is the single most useful record anyone here keeps. Memory reconstructs a titration…
Revisiting: Reading a denial letter as a specification for your appeal Replied, post #68 · Access › Insurance & coverage · 4 Aug 2025 · 29 likes Post #64 put the caveat in the right place and I want to underline it. Keep every document with dates in one place. An appeal months later is assembled from whatever…
A ten-fold dose error caught before injection — one year on Replied, post #45 · Devices › Syringes & needles · 2 Aug 2025 · 0 likes Picking up post #42: that is the part I would want checked first. Ten-fold dose error caught is a good example of a question where the honest answer is boring and the…
How the vendor documentation pages are maintained, and by whom — what changed since Replied, post #33 · Sourcing › Vendor reports · 31 Jul 2025 · 25 likes Post #29 put the caveat in the right place and I want to underline it. Vendor documentation pages sits at the boundary between what this community can usefully discuss…
Second pass at: Journal club: STEP 4 and what a withdrawal design can prove Replied, post #46 · Evidence › Journal club · 29 Jul 2025 · 0 likes Narrowing post #45, because the general version has more than one answer. A conflict-of-interest statement is worth reading aloud and is worth very little as a…
Random versus fixed effects: choosing rather than defaulting Replied, post #16 · Evidence › Meta-analyses · 2 Jul 2025 · 19 likes Number needed to treat from a meta-analysis: can be computed from the pooled estimate if the baseline risk is specified. More interpretable than pooled relative…
The CagriSema phase 2 paper and what a fixed combination buys — the long version Replied, post #153 · Compounds › Cagrilintide & amylin analogues · 20 Jun 2025 · 31 likes Where I part company with post #149, and it is a narrow parting. Gastric emptying: both amylin and GLP-1 slow it, through partly overlapping but distinct mechanisms.…
Airline travel with a temperature-sensitive injectable — what changed since Replied, post #39 · Devices › Cold chain · 15 Jun 2025 · 12 likes Taking post #36 at face value and following it one step further. A parcel sitting in a vehicle or a depot in a hot month is the excursion that matters and the one…
Second pass at: A history of disordered eating: proceeding carefully Replied, post #64 · Wellbeing › Mental health · 5 Jun 2025 · 0 likes I had written a reply contradicting post #62 and deleted it. Here is what survived. Disordered eating history: a history of anorexia, bulimia, or other eating disorders…
The CagriSema phase 2 paper and what a fixed combination buys — the long version Replied, post #13 · Compounds › Cagrilintide & amylin analogues · 4 Jun 2025 · 21 likes Adding the measurement that post #10 says would settle it. The interest in combining it with semaglutide is that two different satiety mechanisms might add. Whether…
Reading a trial's population section before its results — does this still hold? Replied, post #109 · Evidence › Trials · 16 May 2025 · 0 likes A comparator at less than its maximum licensed dose changes what a head-to-head result means. It does not invalidate the trial; it narrows the claim the trial supports.…
A checklist for reading a certificate in under two minutes — does this still hold? Replied, post #3 · Analytics › COA interpretation · 4 May 2025 · 12 likes An itemised related-substances table with retention times says considerably more about the synthesis than a single total. A total tells you how much is not the main…
Certificates issued by the seller versus by a laboratory Replied, post #56 · Analytics › COA interpretation · 22 Apr 2025 · 24 likes Adding thanks rather than a view. I do not have a view worth the space.
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #5 · Evidence › Journal club · 16 Apr 2025 · 0 likes The figures usually contain the finding and the text usually contains the interpretation. Separating them for the first twenty minutes is a discipline worth keeping.
Coming back to: An 18-month record including the parts that went badly Replied, post #40 · Outcomes › Progress reports · 16 Apr 2025 · 0 likes Seasonal patterns: some people report weight loss is slower in winter than summer. Body composition and activity changes might contribute. Noting the season is useful…
An orphaned page with no inbound links Replied, post #26 · Meta › Wiki maintenance · 8 Apr 2025 · 0 likes This is the sort of exchange that makes the archive worth searching.
Second pass at: Retatrutide mass and identity: what a report should show Replied, post #16 · Compounds › Retatrutide · 6 Apr 2025 · 26 likes This is the answer, and the reason it is the answer is the more useful part.
A report I filed that turned out to be wrong, and the correction Replied, post #5 · Sourcing › Vendor reports · 5 Apr 2025 · 0 likes Reports of ordinary results are more valuable than reports of remarkable ones, precisely because only the remarkable ones get posted elsewhere. I have seen it go both…
A promotion I argued against, and why I lost Replied, post #161 · Documentation › Doc review · 4 Apr 2025 · 2 likes Small methodological point on promotion: repeating a measurement is cheap and resolves most of what is being argued about here at no cost to anyone.
Splitting a vial for two laboratories: how to do it without ruining both Replied, post #9 · marked as the solution · Sourcing › Independent verification · 26 Mar 2025 · 12 likes Coming back to post #7, because the follow-up matters more than the original answer. Repeat determination on the same product line months apart is the measurement that…
Reading order for a first week here, and what to skip until later Replied, post #26 · Start Here › Welcome · 6 Mar 2025 · 0 likes The FAQ link in the sidebar is maintained and worth ten hours of forum browsing. It is not comprehensive but it is well indexed for the questions that come up most.
Follow-up: Attributing a new peak: degradation product or excipient? Replied, post #20 · Analytics › Impurities & related substances · 19 Feb 2025 · 0 likes Small correction to my own earlier position on Attributing a new peak. I had the units the wrong way round, which changes the conclusion by an order of magnitude and…
A 10 mg vial reconstituted three different ways, compared — the long version Replied, post #10 · Practice › Reconstitution · 11 Feb 2025 · 0 likes A 10 mg vial reconstituted three different ways: 1 mL diluent gives 10 mg/mL, 2 mL gives 5 mg/mL, 4 mL gives roughly 2.5 mg/mL. The arithmetic is the same; the…
Oxidation and deamidation mass shifts, tabulated Replied, post #44 · Analytics › Mass spectrometry · 28 Jan 2025 · 12 likes Calibration matters: a high-resolution instrument out of calibration can report mass with ppm error large enough to be uninformative. Check when the instrument was last…
Oral semaglutide bioavailability and its variability between people — a second dataset Replied, post #36 · Compounds › Oral incretins · 26 Dec 2024 · 0 likes Answering the question post #32 raises rather than the one it answers. The SOUL trial: cardiovascular outcomes trial for oral semaglutide in people with type 2 diabetes…
Persistent vomiting and the threshold for seeking help — one year on Replied, post #41 · Safety › Adverse events · 22 Dec 2024 · 20 likes That matches what I have seen, for whatever a single anecdote is worth.
[2026 update] New subcategory: rationale and scope Replied, post #80 · Meta › Announcements · 20 Dec 2024 · 27 likes One question about the transition rather than the policy: what happens to topics that are in flight when it takes effect? The announcement is clear about posts and…
[2026 update] How to read a forest plot, properly, from scratch Replied, post #47 · Evidence › Trials · 20 Dec 2024 · 20 likes Post #44 is right about the mechanism and I think understates the practical bit. Risk of bias: structured appraisal of internal validity. Key things to assess:…
Injection-site reactions: describing them precisely enough to be useful Replied, post #65 · Practice › Side effects · 11 Dec 2024 · 11 likes Reading rather than answering, but this is the post I would point somebody at.
Journal club: STEP 4 and what a withdrawal design can prove — one year on Replied, post #8 · Evidence › Journal club · 18 Nov 2024 · 10 likes STEP 1 (N Engl J Med 2021): The pivotal obesity trial for semaglutide and the reference point for most subsequent comparison. Mean weight reduction was substantially…
Follow-up: Dead volume across syringe and needle combinations Replied, post #64 · Devices › Syringes & needles · 12 Nov 2024 · 0 likes Adding a note of thanks rather than an opinion. I did not know most of that.
[2026 update] Journal club: SURPASS-2 and the semaglutide 1 mg comparator Replied, post #29 · Evidence › Journal club · 10 Nov 2024 · 11 likes Two things can be true about SURPASS-2 at once: the mechanism is plausible and the evidence for the size of the effect is thin. Most of the argument here is people…
Time to steady state after a dose increase Replied, post #100 · Pharmacology › Pharmacokinetics · 5 Nov 2024 · 7 likes Post #99 is the version of this I will quote in future. One addition. Renal clearance: these compounds are cleared partly via the kidney. In severe renal impairment,…
US compounding rules and how they changed Replied, post #54 · Regional › North America · 3 Nov 2024 · 0 likes Answering the question post #50 raises rather than the one it answers. Cross-border purchase: buying in the US and bringing to Canada or vice versa involves both…
Critiquing an observational claim about a class effect Started this topic · Evidence › Study critique · 21 Oct 2024 · 5 likes Posting this under the heading it deserves: Critiquing an observational claim about a class effect Everything below is what sits behind that. I was wrong about…
Requesting a page: what makes a good request — what changed since Replied, post #119 · Documentation › Wiki requests · 13 Oct 2024 · 0 likes This follows post #116 rather than contradicting it. Objections to a request belong in the open, and a request that survives an objection is a stronger page for it. The…
Requesting a page: what makes a good request — what changed since Replied, post #92 · Documentation › Wiki requests · 12 Oct 2024 · 0 likes Post #89 is the version of this I will quote in future. One addition. The strongest case for a new document is a question that recurs and has a good answer buried in a…
Second pass at: Sodium, potassium and magnesium when intake drops Replied, post #139 · Nutrition & Training › Hydration & electrolytes · 7 Oct 2024 · 0 likes Orthostatic symptoms: dizziness on standing after lying down can indicate dehydration or electrolyte depletion. Increasing fluids, salt, and potassium usually resolves…
Second pass at: Food noise reducing and the disorientation that can follow Replied, post #16 · Wellbeing › Mental health · 4 Oct 2024 · 0 likes Expectations set by other people's reported trajectories are a documented source of distress, and the trajectories posted are not representative. Written in the hope of…
Coming back to: Deconvolution of a multiply charged envelope Started this topic · Analytics › Mass spectrometry · 23 Sep 2024 · 6 likes On the subject in the title: Deconvolution of a multiply charged envelope Working notes rather than a conclusion. Working through the identity arithmetic and I would…
Second pass at: A field-by-field walk through a certificate of analysis Replied, post #54 · Analytics › COA interpretation · 14 Sep 2024 · 23 likes I had written a reply contradicting post #52 and deleted it. Here is what survived. Asking for the batch record rather than the certificate is a reasonable request and…
A page that has drifted out of date and needs a maintainer Replied, post #5 · Documentation › Wiki requests · 27 Aug 2024 · 17 likes Requests for a page summarising a supplier are declined, because that is what the vendor documentation set is for and it has its own standards. That is the honest state…
When to suspect the method rather than the sample Replied, post #6 · Analytics › Method validation · 26 Aug 2024 · 0 likes Precision and repeatability: within-run and between-run variability of the method. Acceptance criterion is typically a relative standard deviation of ≤2% for area…
Coming back to: Preparing for an appointment: one page, three questions Replied, post #28 · Clinical › Prescriber conversations · 29 Jul 2024 · 0 likes A question phrased as "what would you want to see before considering X" is answerable and is not a request for X. It is worth checking rather than assuming, which costs…
Follow-up: Where the four-week escalation interval comes from, and what it is not Replied, post #30 · Practice › Dosing & titration · 19 Jul 2024 · 2 likes This follows post #29 rather than contradicting it. Concentration and dose get conflated constantly in this subcategory. Changing how much diluent you add changes the…
Journal club: FLOW and the renal composite, component by component Replied, post #74 · Evidence › Journal club · 16 Jul 2024 · 0 likes Taking post #73 at face value and following it one step further. The figures usually contain the finding and the text usually contains the interpretation. Separating…
How this community labels and discusses unrefereed work Replied, post #38 · Evidence › Preprints · 24 Jun 2024 · 15 likes Seconded. It reads as careful rather than confident, which is the right register.
Assessing a warm arrival: the decision process — one year on Replied, post #35 · Sourcing › Logistics · 29 May 2024 · 0 likes My understanding of Assessing a warm arrival is a few years old and may have been superseded. If it has been, I would genuinely like to know rather than keep repeating…