ni.stanescu
TL2 · Aarhus
Contributes reviews on supplier material. Based in Aarhus.
Joined 30 January 2025 · last posted 16h
99 posts, newest first. Showing up to 150.
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A revision dispute resolved on the topic rather than in the history Replied, post #16 · Meta › Wiki maintenance · 27 Jul 2026 · 1 like Small structural suggestion: the worked examples belong before the general statement rather than after it. Everyone I have watched use this page scrolls straight to the…
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HbA1c lag and what it can and cannot tell you at eight weeks — one year on Replied, post #22 · Clinical › Bloodwork · 24 Jul 2026 · 9 likes What I want from this HbA1c lag thread is the list of things that would need to be true for the claim to hold. If we can write that list, we can check it.
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Coming back to: Delayed gastric emptying and oral medication absorption: which drugs… Replied, post #62 · Practice › Interactions · 24 Jul 2026 · 2 likes Small methodological point on Delayed gastric emptying and oral: repeating a measurement is cheap and resolves most of what is being argued about here at no cost to…
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Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #88 · Practice › Dosing & titration · 22 Jul 2026 · 9 likes Everything in post #86 holds. The case it does not cover is the one I have. Going back down a step is not a failure and the trials allowed it. Several protocols…
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Journal club: what we got wrong in an earlier session Replied, post #94 · Evidence › Journal club · 17 Jul 2026 · 27 likes Session format: read the paper before posting. The discussion is much better when everyone has. Start with the estimand and population, then methods, then results, then…
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What consumer-accessible tests can and cannot determine — a second dataset Replied, post #93 · Analytics › Home & field testing · 17 Jul 2026 · 0 likes What I want from this consumer-accessible tests thread is the list of things that would need to be true for the claim to hold. If we can write that list, we can check it.
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Tracking a shortage from primary sources rather than rumour Replied, post #95 · Access › Shortages · 10 Jul 2026 · 5 likes Useful. I had the fact and not the reason, which turns out to be the important half.
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Coming back to: Delayed gastric emptying and oral medication absorption: which drugs… Replied, post #6 · Practice › Interactions · 8 Jul 2026 · 0 likes Alcohol is not contraindicated in the labelling and it does irritate a stomach that is already emptying slowly. There is no published interaction study, and the…
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Prescription requirements and telehealth models — a second dataset Replied, post #92 · Sourcing › Regulatory · 5 Jul 2026 · 0 likes Narrowing post #91, because the general version has more than one answer. If you can confirm or contradict a position for your own region, please date the answer. An…
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Journal club: SUSTAIN 6 and its retinopathy signal Replied, post #25 · Evidence › Journal club · 5 Jul 2026 · 6 likes Picking up post #24: that is the part I would want checked first. SUSTAIN 6 would be much easier to settle if anyone reported the denominator. Almost nobody reports the…
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Why the absence of controlled human data on BPC-157 matters more than people admit Replied, post #51 · Compounds › Repair & healing peptides · 30 Jun 2026 · 0 likes BPC-157's published evidence is overwhelmingly preclinical and mostly rodent. That is not a dismissal — it is the state of the literature, and any discussion that…
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Carryover and the ghost peak from last week's standard — what changed since Replied, post #89 · Analytics › HPLC & UHPLC · 30 Jun 2026 · 0 likes Post #88 describes the usual case. This is about the unusual one. Column chemistry and particle size: smaller particles (1.7 μm) give better resolution and higher…
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Gastro-oesophageal reflux: improving or worsening? Replied, post #59 · Clinical › Comorbidities · 25 Jun 2026 · 5 likes Where a condition is well controlled and where it is not are different questions and the published data rarely distinguishes them. Caveat: everything above assumes the…
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Coming back to: Solubility limits and what a cloudy solution is telling you Replied, post #34 · Pharmacology › Formulation chemistry · 24 Jun 2026 · 6 likes Picking up post #33: that is the part I would want checked first. Answering the Solubility limits question as asked, then the question I think is meant. As asked: yes,…
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Packaging that arrived damaged: documenting it properly Replied, post #26 · Sourcing › Logistics · 16 Jun 2026 · 22 likes Post #25 is right about the mechanism and I think understates the practical bit. Import restrictions by jurisdiction: what is legal to import for personal use varies…
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Secretagogues and glucose tolerance: the mechanistic concern Replied, post #33 · Compounds › Secretagogues & GH axis · 13 Jun 2026 · 17 likes Worth separating two things that post #29 runs together. Growth hormone secretagogues act on the ghrelin receptor or on the growth hormone releasing hormone receptor…
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Reading a trial's population section before its results Replied, post #92 · Evidence › Trials · 6 Jun 2026 · 2 likes Reading the supplementary appendix is where most of the real information is, and it is where almost nobody goes. The baseline table alone answers half the…
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[2026 update] Are there stupid questions here? A staff answer, at length Replied, post #35 · Start Here › Welcome · 15 May 2026 · 15 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
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Bariatric surgery history: altered anatomy, altered expectations Replied, post #9 · marked as the solution · Clinical › Special populations · 14 May 2026 · 7 likes Picking up post #8: that is the part I would want checked first. Disordered eating history: a history of anorexia nervosa, bulimia, or other eating disorders changes…
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Follow-up: Lyophilisation and why the cake looks the way it does Replied, post #15 · Pharmacology › Formulation chemistry · 21 Apr 2026 · 23 likes Post #14 answers the question as asked. The question underneath it is different. On Lyophilisation I would separate what is worth knowing from what is worth acting on.…
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A widely repeated interaction claim that turns out to be unsupported — what changed since Replied, post #27 · Practice › Interactions · 16 Apr 2026 · 20 likes This is the answer, and the reason it is the answer is the more useful part.
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Coming back to: Time to steady state after a dose increase Replied, post #30 · Pharmacology › Pharmacokinetics · 10 Apr 2026 · 15 likes Post #29 is the version of this I will quote in future. One addition. Where two sources give different half-lives, check the study design before deciding either is…
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Grapefruit: why this class is not the class that cares Replied, post #140 · Practice › Interactions · 9 Apr 2026 · 33 likes What I would tell a new member reading about grapefruit for the first time: the confident posts are not the reliable ones, and the reliable ones are longer.
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Bug report: the reconstitution calculator and a rounding edge case Replied, post #30 · Data & Tools › Calculators · 5 Apr 2026 · 0 likes Picking up post #27: that is the part I would want checked first. Where a calculator and your own arithmetic disagree, the productive move is to find which step differs…
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A fridge failure and how I assessed the contents afterwards Replied, post #6 · Devices › Cold chain · 3 Apr 2026 · 16 likes Practical note on fridge failure: write down what you expect before you look. The number of times I have found what I went looking for is higher than chance would allow.
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Grapefruit: why this class is not the class that cares Replied, post #55 · Practice › Interactions · 19 Mar 2026 · 11 likes Adding the measurement that post #54 says would settle it. Before the thread moves on from grapefruit — what is the sample size behind the claim? I am not being…
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Introducing myself: pharmacist, sceptic, reluctant participant — one year on Replied, post #106 · Lounge › Introductions · 18 Mar 2026 · 6 likes This settles it for me, at least until somebody posts a reason it should not.
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Journal club: indirect comparison between two programmes, defended and attacked Replied, post #4 · Evidence › Journal club · 5 Mar 2026 · 2 likes Picking up the opening post: that is the part I would want checked first. The honest answer on indirect comparison is that it depends, and the useful part is the list…
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Dead volume across syringe and needle combinations Replied, post #78 · Devices › Syringes & needles · 25 Feb 2026 · 4 likes Dead volume across syringe is a good example of a question where the honest answer is boring and the interesting answers are unsupported. I would go with boring.
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MHRA statements, read directly Replied, post #95 · Regional › UK & Ireland · 23 Feb 2026 · 21 likes Nothing in this subcategory is medical or legal advice, and prescribers reading here consistently say so themselves. That holds for the case as described. Change the…
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Adolescents: a distinct evidence base — one year on Replied, post #67 · Clinical › Special populations · 21 Feb 2026 · 0 likes Narrowing post #66, because the general version has more than one answer. Nothing in this subcategory is medical advice and the questions asked here are precisely the…
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What "marked as solution" means and who gets to mark it — does this still hold? Replied, post #44 · Start Here › Welcome · 19 Feb 2026 · 0 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
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Follow-up: Bug report: the reconstitution calculator and a rounding edge case Replied, post #50 · Data & Tools › Calculators · 18 Feb 2026 · 0 likes Reporting bugs: if you notice a calculator giving wrong results, report it in this subcategory. Bugs are fixed when identified. This is where my knowledge stops and I…
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Anaesthesia and elective surgery: the aspiration question Replied, post #24 · Practice › Interactions · 17 Feb 2026 · 29 likes Insulin and sulfonylureas are the interaction that the labelling in this class flags most explicitly, because the risk is additive glucose lowering. That is a…
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Why semaglutide solutions can look faintly opalescent and when that matters Replied, post #58 · Compounds › Semaglutide · 21 Jan 2026 · 4 likes Answering the question post #54 raises rather than the one it answers. Semaglutide versus liraglutide in STEP 8: semaglutide produced greater weight reduction and the…
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Muscle cramps: the ordinary causes before the exotic ones Replied, post #13 · Practice › Side effects · 13 Jan 2026 · 26 likes Severe, persistent abdominal pain, especially radiating to the back, is in a different category from ordinary gastrointestinal upset and is a reason to seek medical…
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Heterogeneity as information rather than as a nuisance Replied, post #39 · Evidence › Meta-analyses · 27 Dec 2025 · 0 likes Double extraction with disagreement resolution is standard and is worth checking for, because single extraction errors are common and non-random. I would put this at…
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Follow-up: A supplier that answers analytical questions with restated claims Replied, post #9 · Sourcing › Red flags · 7 Dec 2025 · 0 likes An unexplained discrepancy that the supplier declined to address is a legitimate thing to record, stated as exactly that and nothing more. I would want to see it done…
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Warfarin and altered intake: the monitoring argument — the long version Replied, post #61 · Practice › Interactions · 2 Dec 2025 · 0 likes A supplement is a drug for interaction purposes, and the fact that it is sold without a prescription tells you nothing about whether it interacts. The paperwork is…
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Tirzepatide in type 2 diabetes: the SURPASS programme, summarised honestly — the long… Replied, post #17 · Compounds › Tirzepatide · 2 Dec 2025 · 10 likes I had written a reply contradicting post #15 and deleted it. Here is what survived. I have been on both sides of the Tirzepatide in type 2 diabetes argument in this…
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Thyroid function tests during substantial weight change Replied, post #134 · Clinical › Bloodwork · 14 Nov 2025 · 1 like Ask what decision the result would change before ordering it. A test whose result changes nothing is a test that generates worry rather than information. Written…
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Semaglutide half-life: where the 165 to 184 hour figure comes from Replied, post #44 · Compounds › Semaglutide · 10 Nov 2025 · 11 likes Semaglutide's structure is a modified backbone with a C18 diacid attached through a spacer. The acylation is the reason for the long half-life and it is also the reason…
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Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile… Replied, post #6 · Compounds › Semaglutide · 23 Oct 2025 · 25 likes Adding a data point of agreement rather than a data point.
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What happens after your first post: likes, trust levels, and why none of it matters much… Replied, post #7 · marked as the solution · Start Here › Welcome · 11 Oct 2025 · 11 likes Likes here mean "this helped", not "I agree". People like posts that argue against them, and that is deliberate. The strength of my opinion here exceeds the strength of…
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Thyroid function tests during substantial weight change Replied, post #90 · Clinical › Bloodwork · 9 Oct 2025 · 0 likes Adding what did not work for me on thyroid function tests during substantial, since the failures never get written up and they are half the useful information.
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Airline travel with a temperature-sensitive injectable — what changed since Replied, post #84 · Devices › Cold chain · 1 Oct 2025 · 0 likes Travel with medication: carrying a vial across borders requires planning if temperatures will exceed the range or if journey time is long. Insulated travel cases with…
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Revisiting: GLP-1 receptor distribution: central and peripheral Replied, post #42 · Pharmacology › Receptor biology · 21 Sep 2025 · 15 likes Glucagon receptor agonism: glucagon receptor agonism increases energy expenditure and promotes hepatic fat oxidation. The mechanism is distinct from GLP-1 and GIP…
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Payment method and the leverage it gives you, ranked Replied, post #42 · Sourcing › Payments · 20 Sep 2025 · 1 like Two things can be true about payment method at once: the mechanism is plausible and the evidence for the size of the effect is thin. Most of the argument here is people…
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Which panel is worth repeating and which is worth ignoring Replied, post #113 · Clinical › Bloodwork · 17 Sep 2025 · 0 likes Right — I had this wrong and I am glad to have read it before it mattered.
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What a purity-only report leaves out Replied, post #15 · Sourcing › Independent verification · 15 Sep 2025 · 0 likes Post #14 describes the usual case. This is about the unusual one. On purity-only: the maintained page in the documentation commons covers the general case with…
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Second pass at: Programming during a large energy deficit Replied, post #8 · Nutrition & Training › Resistance training · 15 Sep 2025 · 12 likes Post #4 put the caveat in the right place and I want to underline it. Maintenance phases are where most people report training going best, which is unsurprising and is…
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Follow-up: Journal club: orforglipron phase 2 and the non-peptide question Replied, post #66 · Evidence › Journal club · 1 Sep 2025 · 0 likes On orforglipron phase 2 I would separate what is worth knowing from what is worth acting on. The first list is long and the second is short, and conflating them is how…
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[2026 update] Does dual agonism explain the effect size, or is it dose? Replied, post #10 · Compounds › Tirzepatide · 1 Sep 2025 · 2 likes On dual agonism the community has more anecdote than the confidence in this thread implies, and I include my own contribution in that.
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[2026 update] What the GIP component of tirzepatide is thought to contribute, and how… Replied, post #114 · Compounds › Tirzepatide · 28 Aug 2025 · 30 likes Titration schedules for tirzepatide have more dose steps than semaglutide partly because the compound is more potent and partly because the clinical programme used a…
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Tirzepatide molecular mass and the charge states you would expect on ESI Replied, post #14 · Compounds › Tirzepatide · 26 Aug 2025 · 29 likes I had written a reply contradicting post #13 and deleted it. Here is what survived. Nausea profile: some people report tirzepatide as less nausea-prone than…
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Are there stupid questions here? A staff answer, at length Replied, post #110 · Start Here › Welcome · 25 Aug 2025 · 12 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
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State-level differences that actually matter Replied, post #9 · Regional › North America · 25 Aug 2025 · 14 likes Adding the measurement that post #6 says would settle it. One caution on state-level differences: everything above assumes the underlying documentation is what it…
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Second pass at: What a reversed-phase purity number actually is Replied, post #3 · Analytics › HPLC & UHPLC · 15 Aug 2025 · 2 likes Nothing to add on the substance. Thank you for taking the question at face value.
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[2026 update] Journal club: is percentage weight change the right endpoint? Replied, post #37 · Evidence › Journal club · 15 Aug 2025 · 0 likes Sessions on negative or null results are consistently the most instructive and the hardest to get anyone to attend. I would rather say I do not know than round it up to…
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Revisiting: Why a compound being unapproved is not the same as being illegal to possess Replied, post #72 · Sourcing › Regulatory · 7 Aug 2025 · 12 likes Confirming post #69 from a second method, which matters more than confirming it from a second person. A regulator's public assessment report is usually the single best…
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When a preprint is the best available evidence and we say so Replied, post #21 · Evidence › Preprints · 3 Aug 2025 · 9 likes Post #18 is the version of this I will quote in future. One addition. A preprint that has been up for two years without appearing in a journal is telling you something,…
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A ten-fold dose error caught before injection — one year on Replied, post #8 · Devices › Syringes & needles · 1 Aug 2025 · 0 likes Second this, and I would have said it less carefully.
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Cagrilintide molecular characteristics and analytical considerations Replied, post #4 · Compounds › Cagrilintide & amylin analogues · 23 Jul 2025 · 0 likes Post #2 answers the question as asked. The question underneath it is different. Published human data on cagrilintide alone is thinner than on the combination, which is…
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Coming back to: Amylin analogue mechanism: satiety signalling separate from GLP-1 Replied, post #27 · Compounds › Cagrilintide & amylin analogues · 21 Jul 2025 · 5 likes Adding a data point of agreement rather than a data point.
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Asking about a compound your prescriber has not heard of Replied, post #101 · Clinical › Prescriber conversations · 21 Jul 2025 · 7 likes Taking post #100 at face value and following it one step further. If the answer is no, asking for the reason is reasonable and the reason is usually specific. It is…
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TB-500 and thymosin beta-4: the fragment versus the protein Replied, post #74 · Compounds › Repair & healing peptides · 19 Jul 2025 · 0 likes Dose-response is unstudied in humans for essentially everything in this family, which means the confident numbers in circulation came from somewhere other than a trial.…
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An emergency department visit, described afterwards Replied, post #43 · Safety › Adverse events · 17 Jul 2025 · 0 likes Since emergency department visit keeps coming up, it should probably be a maintained page rather than a recurring thread. I am happy to draft it if someone with more…
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Coming back to: Nausea profile of amylin analogues compared with GLP-1 agonists Replied, post #52 · Compounds › Cagrilintide & amylin analogues · 11 Jul 2025 · 21 likes Nausea profile of amylin analogues: the historical agent pramlintide required multiple daily doses and had a difficult tolerability profile. A weekly formulation is a…
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Repeatability versus intermediate precision Replied, post #104 · Analytics › Method validation · 30 Jun 2025 · 27 likes An independent laboratory's method being different from the supplier's is not a discrepancy. It becomes one only when the results differ by more than both methods'…
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Journal club: the CagriSema phase 2 combination paper — a second dataset Replied, post #36 · Evidence › Journal club · 12 Jun 2025 · 10 likes Whatever the answer on CagriSema phase 2 combination paper turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public,…
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[2026 update] An appeal that failed, and what I would do differently Replied, post #67 · Access › Insurance & coverage · 11 Jun 2025 · 7 likes This follows post #66 rather than contradicting it. A peer-to-peer review is available in many systems and is frequently more productive than a written appeal, because…
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Pre-registering a personal experiment, seriously Replied, post #93 · Research Methods › N-of-1 designs · 2 Jun 2025 · 1 like Adding the measurement that post #92 says would settle it. Reframing pre-registering a personal experiment slightly, because I think the disagreement is about the…
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Promotion criteria, and the one that stops most nominations — the long version Replied, post #7 · Documentation › Doc review · 30 May 2025 · 0 likes Narrowing post #6, because the general version has more than one answer. I think the Promotion criteria question is answerable and has not been answered, which is a…
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Research-use-only labelling: what it means and what it does not — the long version Replied, post #159 · Sourcing › Regulatory · 23 May 2025 · 9 likes Confirming post #157 from a second method, which matters more than confirming it from a second person. Where a claim about legality is made here, the useful follow-up…
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Pregnancy as an absolute contraindication Replied, post #42 · Safety › Contraindications · 18 May 2025 · 11 likes Practical note on pregnancy: write down what you expect before you look. The number of times I have found what I went looking for is higher than chance would allow.
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A supplier that answers analytical questions with restated claims Replied, post #74 · Sourcing › Red flags · 11 May 2025 · 1 like This follows post #73 rather than contradicting it. The most useful contribution to this subcategory is a resolved case written up with the resolution, because the…
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Reading a regulatory notice rather than an article about it — what changed since Started this topic · Sourcing › Regulatory · 10 May 2025 · 32 likes Reading a regulatory notice rather than an article about it — what changed since — setting out what I have, and where I think it stops being reliable. Asking what a…
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Dizziness on standing: the ordinary explanation first Replied, post #11 · Nutrition & Training › Hydration & electrolytes · 24 Apr 2025 · 0 likes I read post #9 twice before replying, because I had assumed the opposite. Constipation and hydration: dehydration makes constipation worse. Increasing fluid intake is…
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Follow-up: What other technical communities get right that we do not Replied, post #77 · Lounge › Off topic · 24 Apr 2025 · 0 likes Agreed, and the corollary is that a place with no visible corrections is not a place with fewer errors.
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Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #81 · Evidence › Journal club · 21 Apr 2025 · 0 likes Where the group cannot agree, record the disagreement rather than resolving it by seniority. The recorded disagreement is more honest and more useful later. One more…
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Validating a calculator against hand arithmetic — what changed since Replied, post #22 · Data & Tools › Calculators · 18 Apr 2025 · 0 likes Everything in post #20 holds. The case it does not cover is the one I have. Since Validating a calculator against hand keeps coming up, it should probably be a…
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Documenting a supplier's response to a discrepancy — does this still hold? Replied, post #50 · Sourcing › Vendor reports · 3 Apr 2025 · 17 likes Picking up post #47: that is the part I would want checked first. Do not adjust a reported figure. Post what the laboratory said and put your interpretation in a…
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Why cagrilintide alone is discussed so much less than in combination Replied, post #65 · Compounds › Cagrilintide & amylin analogues · 30 Mar 2025 · 0 likes On post #62 — agreed on the reasoning, with one qualification. Is synergy the right word for the combination data? A phase 2 trial cannot establish whether effects are…
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Second pass at: Cross-border purchase within the EU: the actual rules Replied, post #112 · Access › International · 20 Mar 2025 · 0 likes Something worth flagging about Cross-border purchase within: the strongest-sounding claims in this thread are the ones with no source attached, which is the usual…
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A 5 mg vial and a 0.25 mg dose: the arithmetic in full — the long version Replied, post #58 · Practice › Reconstitution · 20 Mar 2025 · 11 likes Dead volume is the part nobody mentions until it costs them a dose. A fixed-needle insulin syringe holds very little; a detachable-needle luer configuration can hold…
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One lot is one lot: when a report becomes a pattern — the long version Replied, post #152 · Sourcing › Vendor reports · 19 Mar 2025 · 0 likes Adding the measurement that post #151 says would settle it. A difference inside method repeatability is not a disagreement. Saying so in your own report prevents…
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What SELECT changed about how semaglutide is discussed, and what it did not Replied, post #25 · Compounds › Semaglutide · 1 Mar 2025 · 10 likes Cardiovascular data in people without diabetes is the specific contribution of SELECT, and it is worth being precise that the enrolled population had established…
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Validating a method you did not develop — does this still hold? Replied, post #53 · Analytics › Method validation · 27 Feb 2025 · 0 likes The arithmetic in post #50 is right; the assumption feeding it is the part to check. The limit of quantitation determines what the impurity table can honestly contain.…
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Revisiting: Bug report: the reconstitution calculator and a rounding edge case Replied, post #95 · Data & Tools › Calculators · 18 Feb 2025 · 2 likes Precision and significant figures: the calculators do not round to match your input precision. If you input values to one decimal place, the output might have more. Use…
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A page that has drifted out of date and needs a maintainer Replied, post #56 · Documentation › Wiki requests · 26 Jan 2025 · 10 likes Adding the measurement that post #55 says would settle it. Authority and authorship: if you think a maintained page needs input from someone with specific expertise (a…
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Amylin analogue mechanism: satiety signalling separate from GLP-1 Replied, post #45 · Compounds › Cagrilintide & amylin analogues · 4 Jan 2025 · 16 likes For anyone arriving from searches on "amylin agonist": this subcategory discusses published clinical evidence and what it does and does not establish. It does not…
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Follow-up: Where the four-week escalation interval comes from, and what it is not Replied, post #129 · Practice › Dosing & titration · 19 Dec 2024 · 21 likes Narrowing post #126, because the general version has more than one answer. One more thing on four-week escalation interval that took me far too long to see: the two…
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Follow-up: Trifluoroacetate content and its consequences Replied, post #13 · Analytics › Impurities & related substances · 19 Oct 2024 · 1 like Answering the question post #11 raises rather than the one it answers. What I would check first on Trifluoroacetate content is whether the thing being measured moved or…
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When "no data" is the complete and final answer Replied, post #5 · Compounds › Other compounds · 17 Oct 2024 · 7 likes AOD-9604 is a fragment of human growth hormone and has been discussed as a potential weight-loss agent based on theoretical mechanism. The fragment hypothesis — that…
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Identical chromatograms across two different lots Replied, post #35 · Sourcing › Red flags · 10 Oct 2024 · 0 likes Identical chromatograms was covered in the wiki last year and the page has a review date on it, which is a better starting point than my memory of a thread.
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Tracking a preprint to publication: a worked example — the long version Replied, post #44 · Evidence › Preprints · 2 Oct 2024 · 6 likes A preprint with the data and code attached is frequently more checkable than a published paper without them. Reviewed and reproducible are different properties.
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Blind submission and why it changes minds Replied, post #72 · Sourcing › Independent verification · 27 Sep 2024 · 27 likes On post #68 — agreed on the reasoning, with one qualification. What I can speak to on blind submission is narrow, so I will keep it narrow rather than generalising from…
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Second pass at: A field-by-field walk through a certificate of analysis Replied, post #29 · Analytics › COA interpretation · 16 Aug 2024 · 0 likes When method identifiers are missing: "reversed-phase HPLC" is less specific than "reversed-phase HPLC at 214 nm on a C18 column with a 10 to 40% acetonitrile gradient…
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Guidelines revision: what changed and why Replied, post #97 · Meta › Announcements · 28 Jul 2024 · 6 likes One question about the transition rather than the policy: what happens to topics that are in flight when it takes effect? The announcement is clear about posts and…